| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 428 | 45 | 25 | 0.275 | 0.325 | -2.28 | LF |
| Alexei Ramirez | 411 | 54 | 42 | 0.272 | 0.328 | 0.83 | SS |
| Paul Konerko | 404 | 46 | 69 | 0.310 | 0.386 | 2.98 | 1B-DH |
| Carlos Quentin | 379 | 48 | 56 | 0.261 | 0.356 | 2.39 | RF-DH |
| Alex Rios | 368 | 41 | 23 | 0.212 | 0.258 | -1.56 | CF |
| Adam Dunn | 339 | 27 | 36 | 0.158 | 0.289 | -1.01 | DH-1B |
| Gordon Beckham | 335 | 37 | 30 | 0.252 | 0.301 | -0.50 | 2B |
| A.J. Pierzynski | 332 | 28 | 30 | 0.285 | 0.328 | -1.38 | CR |
| Brent Morel | 231 | 18 | 16 | 0.242 | 0.260 | -1.63 | 3B |
| Brent Lillibridge | 144 | 17 | 15 | 0.250 | 0.333 | 0.12 | RF-1B-CF |
| Omar Vizquel | 133 | 11 | 8 | 0.264 | 0.293 | -1.00 | 3B-2B |
| Mark Teahen | 119 | 10 | 10 | 0.215 | 0.294 | -0.58 | X |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | -0.01 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.23 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Tyler Flowers | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 128.0 | 3.30 | 19 | 0 | X | 1.46 |
| Gavin Floyd | 119.3 | 4.37 | 18 | 1 | X | -1.61 |
| Edwin Jackson | 115.7 | 3.97 | 18 | 0 | X | -0.47 |
| Philip Humber | 113.0 | 3.27 | 17 | 2 | X | 1.40 |
| John Danks | 101.0 | 3.92 | 16 | 0 | X | -0.30 |
| Jake Peavy | 60.7 | 5.19 | 10 | 1 | X | -1.98 |
| Jesse Crain | 43.0 | 2.51 | 0 | 43 | X | 1.29 |
| Sergio Santos | 42.3 | 3.19 | 0 | 38 | X | 0.60 |
| Chris Sale | 42.0 | 3.43 | 0 | 36 | X | 0.36 |
| Matt Thornton | 33.3 | 3.51 | 0 | 36 | X | 0.22 |
| Will Ohman | 30.3 | 3.86 | 0 | 33 | X | -0.04 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.14 |
| Brian Bruney | 15.7 | 2.30 | 0 | 18 | X | 0.55 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.34 |
| Hector Santiago | 5.3 | 0.00 | 0 | 2 | X | 0.47 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | X | -0.40 |
_