| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 441 | 64 | 50 | 0.293 | 0.397 | 2.43 | 2B |
| Adrian Gonzalez | 435 | 67 | 79 | 0.343 | 0.405 | 5.92 | 1B |
| Jacoby Ellsbury | 433 | 70 | 54 | 0.314 | 0.372 | 3.65 | CF |
| Kevin Youkilis | 388 | 54 | 68 | 0.281 | 0.397 | 4.42 | 3B |
| David Ortiz | 362 | 55 | 58 | 0.294 | 0.381 | 4.03 | DH |
| Carl Crawford | 291 | 35 | 33 | 0.246 | 0.278 | 0.85 | LF |
| J.D. Drew | 271 | 23 | 21 | 0.219 | 0.317 | -1.24 | RF |
| Jarrod Saltalamacchia | 219 | 28 | 27 | 0.249 | 0.320 | 1.04 | CR |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.79 | SS-3B |
| Marco Scutaro | 215 | 26 | 17 | 0.259 | 0.330 | -0.14 | SS |
| Jason Varitek | 161 | 20 | 19 | 0.234 | 0.311 | 0.61 | CR |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.38 | CF |
| Josh Reddick | 95 | 19 | 19 | 0.378 | 0.432 | 1.93 | RF-LF |
| Darnell McDonald | 83 | 9 | 13 | 0.160 | 0.241 | 0.51 | RF-LF-CF |
| Drew Sutton | 51 | 9 | 7 | 0.298 | 0.333 | 0.58 | X |
| Yamaico Navarro | 25 | 4 | 2 | 0.174 | 0.240 | 0.09 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 119.0 | 2.12 | 18 | 0 | X | 4.76 |
| Jon Lester | 114.3 | 3.31 | 18 | 0 | X | 1.40 |
| Tim Wakefield | 86.3 | 4.80 | 12 | 9 | X | -1.94 |
| John Lackey | 84.7 | 6.70 | 15 | 0 | X | -5.66 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.67 |
| Alfredo Aceves | 65.3 | 3.44 | 4 | 23 | X | 0.59 |
| Daniel Bard | 47.3 | 1.90 | 0 | 45 | X | 2.13 |
| Jonathan Papelbon | 39.7 | 3.86 | 0 | 40 | X | -0.02 |
| Matt Albers | 39.3 | 2.29 | 0 | 32 | X | 1.42 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.28 |
| Dan Wheeler | 31.7 | 5.40 | 0 | 30 | X | -1.16 |
| Andrew Miller | 31.0 | 4.65 | 6 | 0 | X | -0.59 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.91 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.31 |
| Kyle Weiland | 10.0 | 8.10 | 2 | 0 | X | -1.00 |
| Franklin Morales | 9.3 | 1.93 | 0 | 10 | X | 0.41 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Randy Williams | 2.0 | 13.50 | 0 | 2 | X | -0.45 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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