| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 432 | 64 | 50 | 0.295 | 0.400 | 2.64 | 2B |
| Adrian Gonzalez | 426 | 66 | 79 | 0.340 | 0.404 | 6.03 | 1B |
| Jacoby Ellsbury | 424 | 68 | 52 | 0.312 | 0.370 | 3.44 | CF |
| Kevin Youkilis | 380 | 54 | 68 | 0.285 | 0.403 | 4.60 | 3B |
| David Ortiz | 362 | 55 | 58 | 0.294 | 0.381 | 4.05 | DH |
| Carl Crawford | 283 | 35 | 32 | 0.245 | 0.276 | 0.92 | LF |
| J.D. Drew | 268 | 23 | 21 | 0.217 | 0.317 | -1.17 | RF |
| Jarrod Saltalamacchia | 216 | 27 | 25 | 0.247 | 0.319 | 0.80 | CR |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.80 | SS-3B |
| Marco Scutaro | 208 | 26 | 17 | 0.262 | 0.332 | 0.02 | SS |
| Jason Varitek | 157 | 20 | 18 | 0.241 | 0.318 | 0.60 | CR |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.38 | CF |
| Josh Reddick | 87 | 17 | 19 | 0.347 | 0.402 | 1.90 | RF-LF |
| Darnell McDonald | 83 | 9 | 13 | 0.160 | 0.241 | 0.52 | RF-LF-CF |
| Drew Sutton | 51 | 9 | 7 | 0.298 | 0.333 | 0.58 | X |
| Yamaico Navarro | 21 | 4 | 2 | 0.211 | 0.286 | 0.18 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 119.0 | 2.12 | 18 | 0 | X | 4.75 |
| Jon Lester | 114.3 | 3.31 | 18 | 0 | X | 1.39 |
| Tim Wakefield | 86.3 | 4.80 | 12 | 9 | X | -1.95 |
| John Lackey | 84.7 | 6.70 | 15 | 0 | X | -5.67 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.66 |
| Alfredo Aceves | 63.3 | 3.13 | 4 | 22 | X | 1.04 |
| Daniel Bard | 46.3 | 1.94 | 0 | 44 | X | 2.04 |
| Jonathan Papelbon | 38.7 | 3.96 | 0 | 39 | X | -0.12 |
| Matt Albers | 38.0 | 2.37 | 0 | 31 | X | 1.29 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.29 |
| Dan Wheeler | 31.7 | 5.40 | 0 | 30 | X | -1.16 |
| Andrew Miller | 25.3 | 5.68 | 5 | 0 | X | -1.10 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.91 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.31 |
| Franklin Morales | 9.3 | 1.93 | 0 | 10 | X | 0.41 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.10 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.71 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Kyle Weiland | 4.0 | 13.50 | 1 | 0 | X | -0.90 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Randy Williams | 2.0 | 13.50 | 0 | 2 | X | -0.45 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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