| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 418 | 63 | 46 | 0.291 | 0.397 | 2.33 | 2B |
| Adrian Gonzalez | 412 | 65 | 78 | 0.346 | 0.408 | 6.03 | 1B |
| Jacoby Ellsbury | 410 | 65 | 51 | 0.315 | 0.373 | 3.24 | CF |
| Kevin Youkilis | 367 | 53 | 65 | 0.288 | 0.403 | 4.39 | 3B |
| David Ortiz | 357 | 55 | 58 | 0.298 | 0.384 | 4.08 | DH |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.66 | LF |
| J.D. Drew | 261 | 23 | 21 | 0.223 | 0.322 | -1.07 | RF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.75 | SS-3B |
| Jarrod Saltalamacchia | 211 | 25 | 24 | 0.243 | 0.318 | 0.54 | CR |
| Marco Scutaro | 196 | 24 | 17 | 0.260 | 0.327 | 0.03 | SS |
| Jason Varitek | 150 | 20 | 18 | 0.252 | 0.333 | 0.72 | CR |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.40 | CF |
| Darnell McDonald | 78 | 8 | 10 | 0.151 | 0.205 | 0.19 | RF-LF-CF |
| Josh Reddick | 75 | 14 | 18 | 0.379 | 0.413 | 1.72 | RF-LF |
| Drew Sutton | 49 | 9 | 7 | 0.311 | 0.347 | 0.61 | X |
| Yamaico Navarro | 21 | 4 | 2 | 0.211 | 0.286 | 0.17 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 114.3 | 3.31 | 18 | 0 | X | 1.49 |
| Josh Beckett | 111.0 | 2.27 | 17 | 0 | X | 4.13 |
| John Lackey | 84.7 | 6.70 | 15 | 0 | X | -5.60 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.73 |
| Tim Wakefield | 81.7 | 4.74 | 11 | 9 | X | -1.67 |
| Alfredo Aceves | 60.3 | 3.28 | 4 | 21 | X | 0.82 |
| Daniel Bard | 45.3 | 1.99 | 0 | 43 | X | 1.99 |
| Jonathan Papelbon | 37.7 | 4.06 | 0 | 38 | X | -0.17 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.25 |
| Matt Albers | 36.3 | 2.48 | 0 | 30 | X | 1.17 |
| Dan Wheeler | 29.3 | 5.83 | 0 | 29 | X | -1.35 |
| Andrew Miller | 25.3 | 5.68 | 5 | 0 | X | -1.08 |
| Bobby Jenks | 15.7 | 6.32 | 0 | 18 | X | -0.90 |
| Scott Atchison | 15.3 | 4.70 | 0 | 9 | X | -0.30 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Franklin Morales | 7.0 | 2.57 | 0 | 8 | X | 0.21 |
| Kyle Weiland | 4.0 | 13.50 | 1 | 0 | X | -0.90 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Randy Williams | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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