| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 344 | 56 | 72 | 0.358 | 0.410 | 6.00 | 1B |
| Dustin Pedroia | 344 | 46 | 33 | 0.277 | 0.392 | 0.86 | 2B |
| Jacoby Ellsbury | 340 | 55 | 39 | 0.303 | 0.365 | 2.52 | CF |
| Kevin Youkilis | 307 | 45 | 54 | 0.274 | 0.394 | 3.76 | 3B |
| David Ortiz | 306 | 49 | 48 | 0.311 | 0.389 | 3.57 | DH |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.71 | LF |
| J.D. Drew | 220 | 19 | 18 | 0.233 | 0.332 | -0.87 | RF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.79 | SS-3B |
| Jarrod Saltalamacchia | 170 | 19 | 20 | 0.256 | 0.318 | 0.42 | CR |
| Marco Scutaro | 137 | 15 | 13 | 0.282 | 0.343 | -0.02 | SS |
| Jason Varitek | 127 | 16 | 15 | 0.245 | 0.331 | 0.51 | CR |
| Mike Cameron | 101 | 9 | 9 | 0.156 | 0.218 | -0.29 | CF |
| Darnell McDonald | 45 | 3 | 3 | 0.119 | 0.178 | -0.34 | RF-LF-CF |
| Drew Sutton | 39 | 6 | 5 | 0.297 | 0.308 | 0.31 | X |
| Josh Reddick | 31 | 7 | 8 | 0.462 | 0.516 | 0.90 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 103.3 | 3.66 | 16 | 0 | X | 0.45 |
| Josh Beckett | 92.0 | 1.86 | 14 | 0 | X | 4.26 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.70 |
| Tim Wakefield | 69.3 | 4.54 | 9 | 9 | X | -1.13 |
| John Lackey | 62.3 | 7.36 | 11 | 0 | X | -5.12 |
| Alfredo Aceves | 48.7 | 3.70 | 4 | 15 | X | 0.17 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.27 |
| Daniel Bard | 36.7 | 2.45 | 0 | 34 | X | 1.19 |
| Matt Albers | 29.7 | 3.03 | 0 | 25 | X | 0.56 |
| Jonathan Papelbon | 29.0 | 4.03 | 0 | 29 | X | -0.13 |
| Dan Wheeler | 22.7 | 6.35 | 0 | 23 | X | -1.33 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Andrew Miller | 5.7 | 4.76 | 1 | 0 | X | -0.12 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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