| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 320 | 52 | 65 | 0.348 | 0.403 | 5.36 | 1B |
| Dustin Pedroia | 319 | 42 | 32 | 0.269 | 0.376 | 0.86 | 2B |
| Jacoby Ellsbury | 315 | 51 | 36 | 0.311 | 0.368 | 2.31 | CF |
| David Ortiz | 291 | 48 | 46 | 0.320 | 0.399 | 3.57 | DH |
| Kevin Youkilis | 285 | 44 | 50 | 0.261 | 0.382 | 3.70 | 3B |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.70 | LF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.78 | SS-3B |
| J.D. Drew | 207 | 17 | 18 | 0.230 | 0.329 | -0.81 | RF |
| Jarrod Saltalamacchia | 162 | 18 | 20 | 0.248 | 0.309 | 0.48 | CR |
| Marco Scutaro | 120 | 12 | 12 | 0.278 | 0.342 | -0.08 | SS |
| Jason Varitek | 115 | 15 | 14 | 0.230 | 0.322 | 0.55 | CR |
| Mike Cameron | 93 | 9 | 9 | 0.157 | 0.215 | -0.12 | CF |
| Drew Sutton | 36 | 6 | 5 | 0.314 | 0.306 | 0.38 | X |
| Darnell McDonald | 35 | 3 | 3 | 0.125 | 0.200 | -0.13 | RF-LF-CF |
| Josh Reddick | 19 | 4 | 4 | 0.375 | 0.421 | 0.43 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 97.3 | 3.70 | 15 | 0 | X | 0.31 |
| Josh Beckett | 92.0 | 1.86 | 14 | 0 | X | 4.24 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.68 |
| Tim Wakefield | 63.3 | 4.26 | 8 | 9 | X | -0.63 |
| John Lackey | 59.0 | 7.02 | 10 | 0 | X | -4.38 |
| Alfredo Aceves | 43.7 | 3.30 | 3 | 15 | X | 0.55 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.28 |
| Daniel Bard | 33.7 | 2.67 | 0 | 32 | X | 0.91 |
| Jonathan Papelbon | 28.0 | 4.18 | 0 | 28 | X | -0.22 |
| Matt Albers | 25.0 | 3.24 | 0 | 21 | X | 0.35 |
| Dan Wheeler | 19.3 | 6.98 | 0 | 20 | X | -1.42 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.28 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.79 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 4.3 | 0.00 | 0 | 4 | X | 0.39 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Tommy Hottovy | 2.7 | 6.75 | 0 | 6 | X | -0.18 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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