| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 315 | 50 | 63 | 0.347 | 0.403 | 5.03 | 1B |
| Dustin Pedroia | 314 | 39 | 30 | 0.261 | 0.373 | 0.43 | 2B |
| Jacoby Ellsbury | 310 | 50 | 34 | 0.310 | 0.368 | 2.09 | CF |
| David Ortiz | 286 | 46 | 45 | 0.320 | 0.395 | 3.35 | DH |
| Kevin Youkilis | 280 | 43 | 47 | 0.261 | 0.382 | 3.37 | 3B |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.68 | LF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.77 | SS-3B |
| J.D. Drew | 202 | 16 | 18 | 0.225 | 0.327 | -0.82 | RF |
| Jarrod Saltalamacchia | 158 | 18 | 20 | 0.248 | 0.310 | 0.56 | CR |
| Jason Varitek | 115 | 15 | 14 | 0.230 | 0.322 | 0.55 | CR |
| Marco Scutaro | 115 | 11 | 10 | 0.282 | 0.348 | -0.29 | SS |
| Mike Cameron | 93 | 9 | 9 | 0.157 | 0.215 | -0.13 | CF |
| Drew Sutton | 36 | 6 | 5 | 0.314 | 0.306 | 0.37 | X |
| Darnell McDonald | 35 | 3 | 3 | 0.125 | 0.200 | -0.13 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.41 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 97.3 | 3.70 | 15 | 0 | X | 0.33 |
| Josh Beckett | 92.0 | 1.86 | 14 | 0 | X | 4.26 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.69 |
| John Lackey | 59.0 | 7.02 | 10 | 0 | X | -4.37 |
| Tim Wakefield | 55.3 | 4.39 | 7 | 9 | X | -0.71 |
| Alfredo Aceves | 43.7 | 3.30 | 3 | 15 | X | 0.56 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.27 |
| Daniel Bard | 33.7 | 2.67 | 0 | 32 | X | 0.92 |
| Jonathan Papelbon | 28.0 | 4.18 | 0 | 28 | X | -0.22 |
| Matt Albers | 25.0 | 3.24 | 0 | 21 | X | 0.35 |
| Dan Wheeler | 18.3 | 7.36 | 0 | 19 | X | -1.51 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 4.3 | 0.00 | 0 | 4 | X | 0.39 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Tommy Hottovy | 2.7 | 6.75 | 0 | 6 | X | -0.18 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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