| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 297 | 45 | 61 | 0.347 | 0.397 | 4.68 | 1B |
| Dustin Pedroia | 296 | 36 | 28 | 0.258 | 0.372 | 0.29 | 2B |
| Jacoby Ellsbury | 296 | 49 | 33 | 0.317 | 0.375 | 2.18 | CF |
| Carl Crawford | 270 | 33 | 31 | 0.242 | 0.274 | 0.86 | LF |
| David Ortiz | 270 | 44 | 43 | 0.321 | 0.393 | 3.27 | DH |
| Kevin Youkilis | 265 | 41 | 42 | 0.259 | 0.385 | 2.96 | 3B |
| Jed Lowrie | 212 | 27 | 25 | 0.276 | 0.325 | 0.86 | SS-3B |
| J.D. Drew | 194 | 15 | 16 | 0.229 | 0.330 | -0.96 | RF |
| Jarrod Saltalamacchia | 150 | 17 | 19 | 0.246 | 0.307 | 0.52 | CR |
| Jason Varitek | 108 | 14 | 13 | 0.234 | 0.324 | 0.49 | CR |
| Marco Scutaro | 104 | 11 | 10 | 0.277 | 0.346 | -0.05 | SS |
| Mike Cameron | 87 | 9 | 8 | 0.156 | 0.218 | -0.10 | CF |
| Drew Sutton | 32 | 5 | 5 | 0.290 | 0.281 | 0.36 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.29 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.41 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 89.3 | 3.73 | 14 | 0 | X | 0.28 |
| Josh Beckett | 83.0 | 2.06 | 13 | 0 | X | 3.48 |
| Clay Buchholz | 77.7 | 3.59 | 13 | 0 | X | 0.48 |
| Tim Wakefield | 55.3 | 4.39 | 7 | 9 | X | -0.69 |
| John Lackey | 51.0 | 7.41 | 9 | 0 | X | -4.23 |
| Alfredo Aceves | 42.0 | 3.21 | 3 | 14 | X | 0.63 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.26 |
| Daniel Bard | 32.3 | 2.78 | 0 | 31 | X | 0.81 |
| Jonathan Papelbon | 27.0 | 4.33 | 0 | 27 | X | -0.30 |
| Matt Albers | 24.0 | 3.38 | 0 | 20 | X | 0.27 |
| Dan Wheeler | 18.0 | 7.50 | 0 | 18 | X | -1.53 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 4.0 | 0.00 | 0 | 3 | X | 0.36 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Tommy Hottovy | 2.3 | 7.71 | 0 | 5 | X | -0.21 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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