| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 275 | 31 | 22 | 0.247 | 0.360 | -0.44 | 2B |
| Adrian Gonzalez | 275 | 40 | 54 | 0.335 | 0.385 | 3.87 | 1B |
| Jacoby Ellsbury | 270 | 41 | 31 | 0.306 | 0.363 | 1.67 | CF |
| Carl Crawford | 249 | 31 | 30 | 0.246 | 0.281 | 0.97 | LF |
| David Ortiz | 246 | 39 | 34 | 0.323 | 0.390 | 2.29 | DH |
| Kevin Youkilis | 245 | 37 | 36 | 0.255 | 0.380 | 2.32 | 3B |
| Jed Lowrie | 197 | 26 | 23 | 0.292 | 0.340 | 0.84 | SS-3B |
| J.D. Drew | 180 | 13 | 15 | 0.229 | 0.333 | -0.99 | RF |
| Jarrod Saltalamacchia | 138 | 16 | 18 | 0.236 | 0.297 | 0.56 | CR |
| Jason Varitek | 99 | 10 | 9 | 0.218 | 0.303 | -0.17 | CR |
| Marco Scutaro | 85 | 6 | 8 | 0.247 | 0.318 | -0.39 | SS |
| Mike Cameron | 75 | 8 | 7 | 0.167 | 0.227 | -0.06 | CF |
| Drew Sutton | 29 | 5 | 5 | 0.250 | 0.241 | 0.42 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.29 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.41 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 81.3 | 3.98 | 13 | 0 | X | -0.27 |
| Josh Beckett | 76.0 | 2.01 | 12 | 0 | X | 3.24 |
| Clay Buchholz | 70.7 | 3.82 | 12 | 0 | X | 0.03 |
| Tim Wakefield | 48.3 | 4.84 | 6 | 9 | X | -1.13 |
| John Lackey | 45.0 | 7.60 | 8 | 0 | X | -3.95 |
| Alfredo Aceves | 41.0 | 3.29 | 3 | 13 | X | 0.52 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.27 |
| Daniel Bard | 31.3 | 2.87 | 0 | 30 | X | 0.71 |
| Jonathan Papelbon | 26.0 | 4.50 | 0 | 26 | X | -0.40 |
| Matt Albers | 23.0 | 3.52 | 0 | 19 | X | 0.17 |
| Dan Wheeler | 16.0 | 7.88 | 0 | 16 | X | -1.51 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Tommy Hottovy | 1.3 | 0.00 | 0 | 3 | X | 0.12 |
_