| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 257 | 35 | 48 | 0.335 | 0.381 | 3.02 | 1B |
| Dustin Pedroia | 255 | 29 | 18 | 0.240 | 0.345 | -0.72 | 2B |
| Jacoby Ellsbury | 248 | 37 | 28 | 0.290 | 0.355 | 1.33 | CF |
| Carl Crawford | 229 | 26 | 23 | 0.234 | 0.266 | 0.07 | LF |
| David Ortiz | 229 | 34 | 30 | 0.319 | 0.389 | 1.64 | DH |
| Kevin Youkilis | 225 | 35 | 34 | 0.261 | 0.387 | 2.26 | 3B |
| Jed Lowrie | 186 | 25 | 23 | 0.304 | 0.349 | 0.92 | SS-3B |
| J.D. Drew | 163 | 12 | 10 | 0.225 | 0.337 | -1.30 | RF |
| Jarrod Saltalamacchia | 127 | 13 | 18 | 0.220 | 0.276 | 0.44 | CR |
| Jason Varitek | 91 | 8 | 8 | 0.235 | 0.308 | -0.34 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.42 | SS |
| Mike Cameron | 69 | 8 | 7 | 0.183 | 0.246 | 0.05 | CF |
| Drew Sutton | 27 | 5 | 5 | 0.269 | 0.259 | 0.45 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.30 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.40 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 75.3 | 3.94 | 12 | 0 | X | -0.10 |
| Clay Buchholz | 70.7 | 3.82 | 12 | 0 | X | 0.11 |
| Josh Beckett | 70.0 | 1.80 | 11 | 0 | X | 3.41 |
| Tim Wakefield | 43.0 | 4.40 | 5 | 9 | X | -0.51 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.78 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.23 |
| Alfredo Aceves | 33.3 | 3.51 | 3 | 11 | X | 0.29 |
| Daniel Bard | 28.3 | 3.18 | 0 | 27 | X | 0.47 |
| Jonathan Papelbon | 24.7 | 3.28 | 0 | 24 | X | 0.35 |
| Matt Albers | 20.7 | 3.92 | 0 | 16 | X | -0.01 |
| Dan Wheeler | 15.0 | 8.40 | 0 | 15 | X | -1.58 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.26 |
| Bobby Jenks | 10.7 | 7.59 | 0 | 13 | X | -0.92 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.08 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.73 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
| Tommy Hottovy | 0.3 | 0.00 | 0 | 1 | X | 0.03 |
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