| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 252 | 34 | 47 | 0.329 | 0.377 | 2.93 | 1B |
| Dustin Pedroia | 250 | 29 | 18 | 0.245 | 0.352 | -0.60 | 2B |
| Jacoby Ellsbury | 243 | 36 | 27 | 0.291 | 0.358 | 1.24 | CF |
| David Ortiz | 225 | 33 | 28 | 0.313 | 0.382 | 1.42 | DH |
| Carl Crawford | 225 | 26 | 21 | 0.234 | 0.267 | -0.05 | LF |
| Kevin Youkilis | 220 | 32 | 34 | 0.254 | 0.377 | 2.06 | 3B |
| Jed Lowrie | 182 | 25 | 22 | 0.305 | 0.352 | 0.91 | SS-3B |
| J.D. Drew | 161 | 12 | 10 | 0.228 | 0.342 | -1.25 | RF |
| Jarrod Saltalamacchia | 123 | 12 | 17 | 0.219 | 0.276 | 0.32 | CR |
| Jason Varitek | 91 | 8 | 8 | 0.235 | 0.308 | -0.33 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.42 | SS |
| Mike Cameron | 67 | 7 | 7 | 0.190 | 0.254 | -0.01 | CF |
| Drew Sutton | 27 | 5 | 5 | 0.269 | 0.259 | 0.45 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.30 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.40 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 75.3 | 3.94 | 12 | 0 | X | -0.11 |
| Josh Beckett | 70.0 | 1.80 | 11 | 0 | X | 3.40 |
| Clay Buchholz | 66.0 | 3.41 | 11 | 0 | X | 0.73 |
| Tim Wakefield | 43.0 | 4.40 | 5 | 9 | X | -0.52 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.79 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.24 |
| Alfredo Aceves | 33.3 | 3.51 | 3 | 11 | X | 0.29 |
| Daniel Bard | 27.3 | 3.29 | 0 | 26 | X | 0.38 |
| Jonathan Papelbon | 23.7 | 3.42 | 0 | 23 | X | 0.25 |
| Matt Albers | 20.7 | 3.92 | 0 | 16 | X | -0.02 |
| Dan Wheeler | 15.0 | 8.40 | 0 | 15 | X | -1.58 |
| Scott Atchison | 12.3 | 5.11 | 0 | 6 | X | -0.35 |
| Bobby Jenks | 9.7 | 8.38 | 0 | 12 | X | -1.01 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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