| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 695 | 92 | 56 | 0.275 | 0.331 | -0.41 | SS-2B |
| Adrian Beltre | 641 | 84 | 102 | 0.321 | 0.365 | 4.82 | 3B |
| David Ortiz | 603 | 86 | 102 | 0.266 | 0.367 | 5.90 | DH |
| J.D. Drew | 542 | 69 | 66 | 0.255 | 0.341 | 1.73 | RF |
| Victor Martinez | 538 | 66 | 79 | 0.302 | 0.351 | 2.87 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.61 | 1B |
| Bill Hall | 378 | 43 | 46 | 0.249 | 0.315 | 0.67 | LF-2B |
| Darnell McDonald | 363 | 38 | 35 | 0.269 | 0.325 | -0.67 | CF-RF-LF |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.81 | 2B |
| Mike Lowell | 244 | 23 | 27 | 0.239 | 0.307 | -0.35 | 1B-DH |
| Jed Lowrie | 193 | 32 | 21 | 0.280 | 0.373 | 1.13 | 2B-SS |
| Daniel Nava | 184 | 25 | 26 | 0.247 | 0.353 | 1.13 | LF |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.04 | CF |
| Ryan Kalish | 175 | 25 | 22 | 0.252 | 0.303 | 0.92 | CF-LF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.38 | RF |
| Jason Varitek | 119 | 18 | 16 | 0.231 | 0.294 | 0.84 | CR |
| Eric Patterson | 89 | 9 | 7 | 0.235 | 0.292 | -0.36 | LF |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.35 | CF |
| Kevin Cash | 68 | 1 | 1 | 0.133 | 0.221 | -1.35 | CR |
| Josh Reddick | 62 | 4 | 6 | 0.197 | 0.210 | -0.37 | RF |
| Yamaico Navarro | 46 | 2 | 5 | 0.143 | 0.174 | -0.32 | SS |
| Lars Anderson | 40 | 4 | 3 | 0.212 | 0.350 | -0.18 | 1B |
| Jarrod Saltalamacchia | 25 | 2 | 1 | 0.158 | 0.360 | -0.26 | X |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Felipe Lopez | 16 | 2 | 1 | 0.267 | 0.312 | -0.05 | 3B-2B-SS |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 208.0 | 3.25 | 32 | 0 | X | 3.87 |
| John Lackey | 207.3 | 4.47 | 32 | 0 | X | -2.07 |
| Clay Buchholz | 173.7 | 2.33 | 28 | 0 | X | 6.93 |
| Daisuke Matsuzaka | 153.7 | 4.69 | 25 | 0 | X | -2.31 |
| Tim Wakefield | 140.0 | 5.34 | 19 | 13 | X | -4.23 |
| Josh Beckett | 127.7 | 5.78 | 21 | 0 | X | -5.18 |
| Daniel Bard | 74.3 | 1.94 | 0 | 72 | X | 3.65 |
| Jonathan Papelbon | 66.0 | 3.95 | 0 | 64 | X | 0.14 |
| Scott Atchison | 60.0 | 4.35 | 1 | 42 | X | -0.43 |
| Hideki Okajima | 46.0 | 4.50 | 0 | 56 | X | -0.49 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.68 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.42 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.16 |
| Michael Bowden | 15.3 | 5.28 | 0 | 14 | X | -0.44 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 26 | X | -0.03 |
| Robert Manuel | 12.7 | 4.26 | 0 | 10 | X | -0.07 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 5.7 | 4.76 | 0 | 6 | X | -0.10 |
| Rich Hill | 4.0 | 0.00 | 0 | 5 | X | 0.38 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Matt Fox | 1.7 | 10.80 | 0 | 3 | X | -0.26 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
_