| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 692 | 91 | 56 | 0.273 | 0.329 | -0.51 | SS-2B |
| Adrian Beltre | 638 | 84 | 102 | 0.323 | 0.367 | 4.83 | 3B |
| David Ortiz | 597 | 85 | 102 | 0.268 | 0.365 | 5.88 | DH |
| J.D. Drew | 537 | 69 | 66 | 0.256 | 0.343 | 1.80 | RF |
| Victor Martinez | 530 | 64 | 77 | 0.300 | 0.349 | 2.59 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.57 | 1B |
| Bill Hall | 368 | 42 | 46 | 0.243 | 0.307 | 0.76 | LF-2B |
| Darnell McDonald | 354 | 38 | 35 | 0.272 | 0.331 | -0.49 | CF-RF-LF |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.78 | 2B |
| Mike Lowell | 237 | 22 | 25 | 0.226 | 0.295 | -0.53 | 1B-DH |
| Jed Lowrie | 182 | 30 | 21 | 0.283 | 0.374 | 1.16 | 2B-SS |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.05 | CF |
| Daniel Nava | 174 | 24 | 24 | 0.240 | 0.345 | 1.03 | LF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.37 | RF |
| Ryan Kalish | 165 | 23 | 22 | 0.250 | 0.291 | 0.92 | CF-LF |
| Jason Varitek | 119 | 18 | 16 | 0.231 | 0.294 | 0.83 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.36 | CF |
| Eric Patterson | 82 | 9 | 6 | 0.243 | 0.305 | -0.31 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.32 | CR |
| Josh Reddick | 57 | 4 | 6 | 0.214 | 0.228 | -0.26 | RF |
| Yamaico Navarro | 37 | 2 | 4 | 0.147 | 0.189 | -0.22 | SS |
| Lars Anderson | 31 | 3 | 2 | 0.222 | 0.323 | -0.19 | 1B |
| Jarrod Saltalamacchia | 25 | 2 | 1 | 0.158 | 0.360 | -0.26 | X |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Felipe Lopez | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | 3B-2B-SS |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 207.3 | 4.47 | 32 | 0 | X | -2.02 |
| Jon Lester | 204.0 | 2.96 | 31 | 0 | X | 5.22 |
| Clay Buchholz | 173.7 | 2.33 | 28 | 0 | X | 6.97 |
| Daisuke Matsuzaka | 148.7 | 4.72 | 24 | 0 | X | -2.32 |
| Tim Wakefield | 135.0 | 5.20 | 18 | 13 | X | -3.61 |
| Josh Beckett | 127.7 | 5.78 | 21 | 0 | X | -5.15 |
| Daniel Bard | 73.3 | 1.96 | 0 | 71 | X | 3.57 |
| Jonathan Papelbon | 65.0 | 4.02 | 0 | 63 | X | 0.06 |
| Scott Atchison | 58.3 | 4.17 | 1 | 41 | X | -0.15 |
| Hideki Okajima | 44.7 | 4.63 | 0 | 55 | X | -0.61 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.67 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.41 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.16 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 25 | X | -0.03 |
| Michael Bowden | 12.7 | 6.39 | 0 | 12 | X | -0.69 |
| Robert Manuel | 9.7 | 5.59 | 0 | 8 | X | -0.35 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 4.3 | 6.23 | 0 | 4 | X | -0.22 |
| Rich Hill | 2.0 | 0.00 | 0 | 3 | X | 0.19 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Matt Fox | 1.7 | 10.80 | 0 | 3 | X | -0.26 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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