| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 678 | 87 | 56 | 0.271 | 0.329 | -0.63 | SS-2B |
| Adrian Beltre | 621 | 82 | 99 | 0.320 | 0.366 | 4.67 | 3B |
| David Ortiz | 579 | 84 | 98 | 0.265 | 0.364 | 5.75 | DH |
| J.D. Drew | 525 | 68 | 65 | 0.260 | 0.347 | 1.85 | RF |
| Victor Martinez | 512 | 61 | 74 | 0.299 | 0.350 | 2.36 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.56 | 1B |
| Bill Hall | 360 | 40 | 45 | 0.242 | 0.303 | 0.62 | LF-2B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.77 | 2B |
| Darnell McDonald | 348 | 38 | 35 | 0.273 | 0.333 | -0.37 | CF-RF-LF |
| Mike Lowell | 229 | 21 | 23 | 0.224 | 0.297 | -0.66 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.06 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.36 | RF |
| Daniel Nava | 170 | 24 | 24 | 0.245 | 0.347 | 1.12 | LF |
| Jed Lowrie | 167 | 30 | 20 | 0.281 | 0.371 | 1.40 | 2B-SS |
| Ryan Kalish | 154 | 22 | 22 | 0.254 | 0.299 | 1.07 | CF-LF |
| Jason Varitek | 115 | 18 | 16 | 0.240 | 0.304 | 0.92 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.36 | CF |
| Eric Patterson | 77 | 9 | 6 | 0.257 | 0.312 | -0.20 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 54 | 4 | 6 | 0.226 | 0.241 | -0.20 | RF |
| Yamaico Navarro | 37 | 2 | 4 | 0.147 | 0.189 | -0.22 | SS |
| Lars Anderson | 27 | 3 | 2 | 0.261 | 0.370 | -0.10 | 1B |
| Jarrod Saltalamacchia | 25 | 2 | 1 | 0.158 | 0.360 | -0.26 | X |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 204.0 | 2.96 | 31 | 0 | X | 5.26 |
| John Lackey | 201.3 | 4.51 | 31 | 0 | X | -2.14 |
| Clay Buchholz | 165.7 | 2.39 | 27 | 0 | X | 6.46 |
| Daisuke Matsuzaka | 140.7 | 4.86 | 23 | 0 | X | -2.63 |
| Tim Wakefield | 134.0 | 5.17 | 18 | 12 | X | -3.47 |
| Josh Beckett | 121.7 | 5.77 | 20 | 0 | X | -4.85 |
| Daniel Bard | 72.3 | 1.87 | 0 | 70 | X | 3.70 |
| Jonathan Papelbon | 64.0 | 3.94 | 0 | 62 | X | 0.18 |
| Scott Atchison | 57.3 | 4.08 | 1 | 39 | X | -0.03 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Hideki Okajima | 43.3 | 4.57 | 0 | 53 | X | -0.51 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 24 | X | -0.03 |
| Michael Bowden | 12.0 | 6.00 | 0 | 11 | X | -0.54 |
| Robert Manuel | 9.7 | 5.59 | 0 | 8 | X | -0.34 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 4.3 | 6.23 | 0 | 4 | X | -0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Matt Fox | 1.7 | 10.80 | 0 | 2 | X | -0.26 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Rich Hill | 1.0 | 0.00 | 0 | 2 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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