| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 658 | 86 | 53 | 0.273 | 0.331 | -0.59 | SS-2B |
| Adrian Beltre | 599 | 82 | 98 | 0.329 | 0.374 | 5.07 | 3B |
| David Ortiz | 557 | 81 | 92 | 0.263 | 0.364 | 5.31 | DH |
| J.D. Drew | 502 | 64 | 62 | 0.257 | 0.349 | 1.64 | RF |
| Victor Martinez | 485 | 57 | 71 | 0.290 | 0.336 | 2.25 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.56 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.77 | 2B |
| Bill Hall | 344 | 38 | 41 | 0.235 | 0.299 | 0.36 | LF-2B |
| Darnell McDonald | 340 | 37 | 33 | 0.272 | 0.332 | -0.50 | CF-RF-LF |
| Mike Lowell | 214 | 17 | 23 | 0.229 | 0.299 | -0.74 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.06 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.36 | RF |
| Daniel Nava | 158 | 22 | 22 | 0.246 | 0.342 | 0.97 | LF |
| Jed Lowrie | 146 | 24 | 17 | 0.266 | 0.356 | 0.94 | 2B-SS |
| Ryan Kalish | 135 | 20 | 21 | 0.246 | 0.281 | 1.19 | CF-LF |
| Jason Varitek | 111 | 18 | 16 | 0.250 | 0.315 | 1.01 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.36 | CF |
| Eric Patterson | 76 | 9 | 6 | 0.261 | 0.316 | -0.18 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 48 | 3 | 5 | 0.234 | 0.250 | -0.27 | RF |
| Yamaico Navarro | 30 | 1 | 3 | 0.107 | 0.133 | -0.27 | SS |
| Jarrod Saltalamacchia | 25 | 2 | 1 | 0.158 | 0.360 | -0.26 | X |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Lars Anderson | 18 | 2 | 2 | 0.267 | 0.389 | 0.00 | 1B |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 194.3 | 4.63 | 30 | 0 | X | -2.59 |
| Jon Lester | 190.0 | 3.17 | 29 | 0 | X | 3.93 |
| Clay Buchholz | 159.7 | 2.48 | 26 | 0 | X | 5.89 |
| Daisuke Matsuzaka | 134.3 | 4.82 | 22 | 0 | X | -2.39 |
| Tim Wakefield | 134.0 | 5.17 | 18 | 12 | X | -3.47 |
| Josh Beckett | 115.0 | 5.71 | 19 | 0 | X | -4.43 |
| Daniel Bard | 68.7 | 1.83 | 0 | 66 | X | 3.57 |
| Jonathan Papelbon | 61.0 | 3.39 | 0 | 59 | X | 0.95 |
| Scott Atchison | 55.7 | 3.40 | 1 | 36 | X | 0.86 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Hideki Okajima | 40.7 | 4.65 | 0 | 50 | X | -0.56 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 24 | X | -0.03 |
| Michael Bowden | 11.0 | 6.55 | 0 | 10 | X | -0.64 |
| Robert Manuel | 9.7 | 5.59 | 0 | 8 | X | -0.34 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 3.3 | 8.10 | 0 | 3 | X | -0.31 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Rich Hill | 1.0 | 0.00 | 0 | 2 | X | 0.09 |
| Matt Fox | 0.7 | 13.50 | 0 | 1 | X | -0.15 |
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