| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 635 | 81 | 53 | 0.274 | 0.331 | -0.58 | SS-2B |
| Adrian Beltre | 577 | 76 | 96 | 0.326 | 0.369 | 4.75 | 3B |
| David Ortiz | 537 | 77 | 88 | 0.260 | 0.363 | 4.94 | DH |
| J.D. Drew | 498 | 64 | 61 | 0.257 | 0.347 | 1.64 | RF |
| Victor Martinez | 462 | 54 | 63 | 0.292 | 0.340 | 1.63 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.56 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.77 | 2B |
| Bill Hall | 336 | 38 | 41 | 0.237 | 0.301 | 0.54 | LF-2B |
| Darnell McDonald | 328 | 35 | 33 | 0.273 | 0.335 | -0.43 | CF-RF-LF |
| Mike Lowell | 210 | 17 | 22 | 0.223 | 0.295 | -0.75 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.06 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.36 | RF |
| Daniel Nava | 148 | 20 | 20 | 0.248 | 0.345 | 0.79 | LF |
| Jed Lowrie | 130 | 20 | 13 | 0.250 | 0.354 | 0.47 | 2B-SS |
| Ryan Kalish | 116 | 17 | 18 | 0.252 | 0.293 | 1.00 | CF-LF |
| Jason Varitek | 107 | 17 | 16 | 0.258 | 0.318 | 1.00 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.36 | CF |
| Eric Patterson | 76 | 9 | 6 | 0.261 | 0.316 | -0.18 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 36 | 3 | 3 | 0.257 | 0.278 | -0.20 | RF |
| Yamaico Navarro | 24 | 0 | 2 | 0.091 | 0.125 | -0.34 | SS |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Jarrod Saltalamacchia | 19 | 2 | 1 | 0.200 | 0.368 | -0.12 | X |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Lars Anderson | 11 | 2 | 1 | 0.222 | 0.364 | 0.06 | 1B |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 190.0 | 4.45 | 29 | 0 | X | -1.74 |
| Jon Lester | 182.0 | 3.26 | 28 | 0 | X | 3.38 |
| Clay Buchholz | 152.7 | 2.53 | 25 | 0 | X | 5.43 |
| Tim Wakefield | 131.7 | 5.26 | 18 | 11 | X | -3.70 |
| Daisuke Matsuzaka | 128.3 | 4.70 | 21 | 0 | X | -1.91 |
| Josh Beckett | 108.0 | 5.83 | 18 | 0 | X | -4.47 |
| Daniel Bard | 66.7 | 1.89 | 0 | 64 | X | 3.37 |
| Jonathan Papelbon | 60.0 | 3.30 | 0 | 58 | X | 1.06 |
| Scott Atchison | 54.7 | 3.46 | 1 | 35 | X | 0.77 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Hideki Okajima | 37.0 | 5.11 | 0 | 47 | X | -0.91 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 24 | X | -0.03 |
| Michael Bowden | 10.0 | 4.50 | 0 | 8 | X | -0.10 |
| Robert Manuel | 9.7 | 5.59 | 0 | 8 | X | -0.34 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 3.3 | 8.10 | 0 | 3 | X | -0.31 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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