| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 625 | 80 | 52 | 0.275 | 0.331 | -0.60 | SS-2B |
| Adrian Beltre | 568 | 74 | 95 | 0.323 | 0.364 | 4.60 | 3B |
| David Ortiz | 532 | 76 | 88 | 0.259 | 0.363 | 4.91 | DH |
| J.D. Drew | 494 | 63 | 59 | 0.252 | 0.342 | 1.38 | RF |
| Victor Martinez | 452 | 53 | 63 | 0.293 | 0.341 | 1.72 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.75 | 2B |
| Bill Hall | 330 | 38 | 41 | 0.242 | 0.306 | 0.66 | LF-2B |
| Darnell McDonald | 319 | 35 | 33 | 0.274 | 0.335 | -0.24 | CF-RF-LF |
| Mike Lowell | 202 | 16 | 22 | 0.231 | 0.297 | -0.68 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Daniel Nava | 147 | 20 | 20 | 0.250 | 0.347 | 0.80 | LF |
| Jed Lowrie | 124 | 19 | 13 | 0.255 | 0.363 | 0.49 | 2B-SS |
| Ryan Kalish | 110 | 17 | 15 | 0.238 | 0.282 | 0.82 | CF-LF |
| Jason Varitek | 107 | 17 | 16 | 0.258 | 0.318 | 0.99 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.37 | CF |
| Eric Patterson | 76 | 9 | 6 | 0.261 | 0.316 | -0.18 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 36 | 3 | 3 | 0.257 | 0.278 | -0.20 | RF |
| Yamaico Navarro | 22 | 0 | 2 | 0.100 | 0.136 | -0.30 | SS |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Jarrod Saltalamacchia | 15 | 2 | 1 | 0.273 | 0.467 | -0.03 | X |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Lars Anderson | 11 | 2 | 1 | 0.222 | 0.364 | 0.06 | 1B |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 183.0 | 4.48 | 28 | 0 | X | -1.75 |
| Jon Lester | 182.0 | 3.26 | 28 | 0 | X | 3.41 |
| Clay Buchholz | 152.7 | 2.53 | 25 | 0 | X | 5.46 |
| Tim Wakefield | 131.7 | 5.26 | 18 | 11 | X | -3.68 |
| Daisuke Matsuzaka | 128.3 | 4.70 | 21 | 0 | X | -1.89 |
| Josh Beckett | 102.0 | 5.91 | 17 | 0 | X | -4.39 |
| Daniel Bard | 66.0 | 1.77 | 0 | 63 | X | 3.53 |
| Jonathan Papelbon | 59.0 | 3.36 | 0 | 57 | X | 0.98 |
| Scott Atchison | 52.7 | 3.59 | 1 | 34 | X | 0.59 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.39 |
| Hideki Okajima | 36.7 | 5.15 | 0 | 46 | X | -0.93 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 13.0 | 4.15 | 0 | 24 | X | -0.03 |
| Michael Bowden | 10.0 | 4.50 | 0 | 8 | X | -0.10 |
| Robert Manuel | 9.7 | 5.59 | 0 | 8 | X | -0.34 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Coello | 3.3 | 8.10 | 0 | 3 | X | -0.31 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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