| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 620 | 77 | 49 | 0.270 | 0.327 | -1.12 | SS-2B |
| Adrian Beltre | 559 | 73 | 93 | 0.322 | 0.363 | 4.49 | 3B |
| David Ortiz | 523 | 73 | 87 | 0.261 | 0.363 | 4.69 | DH |
| J.D. Drew | 486 | 63 | 59 | 0.254 | 0.346 | 1.56 | RF |
| Victor Martinez | 443 | 52 | 61 | 0.292 | 0.339 | 1.61 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.75 | 2B |
| Bill Hall | 322 | 38 | 41 | 0.247 | 0.311 | 0.84 | LF-2B |
| Darnell McDonald | 318 | 35 | 33 | 0.275 | 0.336 | -0.22 | CF-RF-LF |
| Mike Lowell | 202 | 16 | 22 | 0.231 | 0.297 | -0.69 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Daniel Nava | 147 | 20 | 20 | 0.250 | 0.347 | 0.80 | LF |
| Jed Lowrie | 121 | 19 | 13 | 0.260 | 0.364 | 0.56 | 2B-SS |
| Jason Varitek | 107 | 17 | 16 | 0.258 | 0.318 | 0.99 | CR |
| Ryan Kalish | 102 | 16 | 14 | 0.247 | 0.294 | 0.79 | CF-LF |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.37 | CF |
| Eric Patterson | 75 | 9 | 6 | 0.250 | 0.307 | -0.16 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 28 | 2 | 3 | 0.185 | 0.214 | -0.12 | RF |
| Yamaico Navarro | 22 | 0 | 2 | 0.100 | 0.136 | -0.30 | SS |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Jarrod Saltalamacchia | 14 | 2 | 1 | 0.300 | 0.500 | -0.01 | X |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Lars Anderson | 5 | 1 | 0 | 0.000 | 0.200 | -0.01 | 1B |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 183.0 | 4.48 | 28 | 0 | X | -1.74 |
| Jon Lester | 182.0 | 3.26 | 28 | 0 | X | 3.41 |
| Clay Buchholz | 151.7 | 2.25 | 24 | 0 | X | 6.41 |
| Daisuke Matsuzaka | 128.3 | 4.70 | 21 | 0 | X | -1.89 |
| Tim Wakefield | 126.7 | 5.19 | 17 | 11 | X | -3.31 |
| Josh Beckett | 102.0 | 5.91 | 17 | 0 | X | -4.39 |
| Daniel Bard | 65.0 | 1.80 | 0 | 62 | X | 3.44 |
| Jonathan Papelbon | 59.0 | 3.36 | 0 | 57 | X | 0.98 |
| Scott Atchison | 50.7 | 3.73 | 1 | 33 | X | 0.40 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.65 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.39 |
| Hideki Okajima | 35.7 | 5.30 | 0 | 45 | X | -1.03 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 11.0 | 4.91 | 0 | 23 | X | -0.22 |
| Robert Manuel | 8.7 | 6.23 | 0 | 7 | X | -0.44 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Michael Bowden | 8.0 | 5.62 | 0 | 7 | X | -0.29 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Robert Coello | 1.3 | 20.25 | 0 | 2 | X | -0.50 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
_