| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 617 | 76 | 49 | 0.271 | 0.329 | -1.15 | SS-2B |
| Adrian Beltre | 556 | 73 | 93 | 0.324 | 0.365 | 4.57 | 3B |
| David Ortiz | 521 | 73 | 87 | 0.262 | 0.365 | 4.75 | DH |
| J.D. Drew | 484 | 63 | 59 | 0.255 | 0.347 | 1.61 | RF |
| Victor Martinez | 441 | 52 | 59 | 0.288 | 0.336 | 1.45 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.75 | 2B |
| Bill Hall | 318 | 38 | 41 | 0.247 | 0.311 | 0.94 | LF-2B |
| Darnell McDonald | 313 | 33 | 32 | 0.274 | 0.332 | -0.42 | CF-RF-LF |
| Mike Lowell | 199 | 16 | 22 | 0.235 | 0.302 | -0.61 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Daniel Nava | 147 | 20 | 20 | 0.250 | 0.347 | 0.80 | LF |
| Jed Lowrie | 117 | 19 | 12 | 0.260 | 0.368 | 0.55 | 2B-SS |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Ryan Kalish | 102 | 16 | 14 | 0.247 | 0.294 | 0.79 | CF-LF |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.37 | CF |
| Eric Patterson | 74 | 9 | 6 | 0.254 | 0.311 | -0.14 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Yamaico Navarro | 19 | 0 | 2 | 0.111 | 0.105 | -0.23 | SS |
| Jarrod Saltalamacchia | 12 | 1 | 0 | 0.222 | 0.417 | -0.17 | X |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Lars Anderson | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | 1B |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 183.0 | 4.48 | 28 | 0 | X | -1.75 |
| Jon Lester | 182.0 | 3.26 | 28 | 0 | X | 3.40 |
| Clay Buchholz | 151.7 | 2.25 | 24 | 0 | X | 6.41 |
| Tim Wakefield | 126.7 | 5.19 | 17 | 11 | X | -3.31 |
| Daisuke Matsuzaka | 123.7 | 4.29 | 20 | 0 | X | -0.66 |
| Josh Beckett | 102.0 | 5.91 | 17 | 0 | X | -4.39 |
| Daniel Bard | 65.0 | 1.80 | 0 | 62 | X | 3.44 |
| Jonathan Papelbon | 59.0 | 3.36 | 0 | 57 | X | 0.98 |
| Scott Atchison | 50.7 | 3.73 | 1 | 33 | X | 0.40 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.39 |
| Hideki Okajima | 35.7 | 5.30 | 0 | 45 | X | -1.03 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 11.0 | 2.45 | 0 | 22 | X | 0.41 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.3 | 3.68 | 0 | 6 | X | 0.07 |
| Michael Bowden | 6.0 | 7.50 | 0 | 6 | X | -0.48 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Robert Coello | 0.3 | 81.00 | 0 | 1 | X | -0.60 |
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