| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 617 | 76 | 49 | 0.271 | 0.329 | -1.15 | SS-2B |
| Adrian Beltre | 551 | 71 | 92 | 0.324 | 0.363 | 4.37 | 3B |
| David Ortiz | 516 | 72 | 84 | 0.259 | 0.360 | 4.44 | DH |
| J.D. Drew | 479 | 62 | 59 | 0.253 | 0.344 | 1.62 | RF |
| Victor Martinez | 436 | 50 | 57 | 0.289 | 0.335 | 1.15 | CR-1B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.75 | 2B |
| Bill Hall | 318 | 38 | 41 | 0.247 | 0.311 | 0.94 | LF-2B |
| Darnell McDonald | 313 | 33 | 32 | 0.274 | 0.332 | -0.42 | CF-RF-LF |
| Mike Lowell | 199 | 16 | 22 | 0.235 | 0.302 | -0.61 | 1B-DH |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Daniel Nava | 142 | 18 | 20 | 0.248 | 0.338 | 0.70 | LF |
| Jed Lowrie | 112 | 18 | 11 | 0.271 | 0.375 | 0.45 | 2B-SS |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Ryan Kalish | 98 | 13 | 10 | 0.233 | 0.276 | 0.15 | CF-LF |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.37 | CF |
| Eric Patterson | 74 | 9 | 6 | 0.254 | 0.311 | -0.14 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Yamaico Navarro | 15 | 0 | 1 | 0.133 | 0.133 | -0.24 | SS |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Jarrod Saltalamacchia | 12 | 1 | 0 | 0.222 | 0.417 | -0.17 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 183.0 | 4.48 | 28 | 0 | X | -1.76 |
| Jon Lester | 176.0 | 3.27 | 27 | 0 | X | 3.24 |
| Clay Buchholz | 151.7 | 2.25 | 24 | 0 | X | 6.40 |
| Tim Wakefield | 126.7 | 5.19 | 17 | 11 | X | -3.32 |
| Daisuke Matsuzaka | 123.7 | 4.29 | 20 | 0 | X | -0.67 |
| Josh Beckett | 102.0 | 5.91 | 17 | 0 | X | -4.40 |
| Daniel Bard | 65.0 | 1.80 | 0 | 62 | X | 3.43 |
| Jonathan Papelbon | 59.0 | 3.36 | 0 | 57 | X | 0.97 |
| Scott Atchison | 49.0 | 3.86 | 1 | 32 | X | 0.23 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Hideki Okajima | 34.7 | 5.45 | 0 | 44 | X | -1.12 |
| Felix Doubront | 25.0 | 4.32 | 3 | 9 | X | -0.15 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 11.0 | 2.45 | 0 | 21 | X | 0.41 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.3 | 3.68 | 0 | 6 | X | 0.07 |
| Michael Bowden | 6.0 | 7.50 | 0 | 6 | X | -0.48 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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