| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 578 | 74 | 44 | 0.275 | 0.334 | -0.96 | SS-2B |
| Adrian Beltre | 513 | 67 | 87 | 0.324 | 0.365 | 4.32 | 3B |
| David Ortiz | 477 | 69 | 79 | 0.262 | 0.367 | 4.52 | DH |
| J.D. Drew | 443 | 60 | 58 | 0.258 | 0.350 | 2.15 | RF |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.54 | 1B |
| Victor Martinez | 397 | 44 | 51 | 0.280 | 0.330 | 0.80 | CR-1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.76 | 2B |
| Bill Hall | 296 | 37 | 40 | 0.243 | 0.311 | 1.25 | LF-2B |
| Darnell McDonald | 291 | 30 | 32 | 0.272 | 0.330 | -0.21 | CF-RF-LF |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.06 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Mike Lowell | 166 | 13 | 21 | 0.233 | 0.313 | -0.27 | 1B-DH |
| Daniel Nava | 124 | 16 | 19 | 0.269 | 0.363 | 0.81 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Jed Lowrie | 84 | 14 | 8 | 0.282 | 0.393 | 0.37 | 2B-SS |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.37 | CF |
| Ryan Kalish | 78 | 11 | 8 | 0.233 | 0.256 | 0.19 | CF-LF |
| Eric Patterson | 74 | 9 | 6 | 0.254 | 0.311 | -0.13 | LF |
| Kevin Cash | 62 | 1 | 0 | 0.143 | 0.226 | -1.33 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Jarrod Saltalamacchia | 8 | 1 | 0 | 0.333 | 0.500 | -0.08 | X |
| Yamaico Navarro | 8 | 0 | 0 | 0.125 | 0.125 | -0.18 | SS |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 169.7 | 4.51 | 26 | 0 | X | -1.77 |
| Jon Lester | 163.0 | 3.26 | 25 | 0 | X | 3.06 |
| Clay Buchholz | 139.3 | 2.26 | 22 | 0 | X | 5.85 |
| Tim Wakefield | 124.7 | 5.27 | 17 | 10 | X | -3.52 |
| Daisuke Matsuzaka | 118.0 | 4.19 | 19 | 0 | X | -0.37 |
| Josh Beckett | 88.7 | 6.50 | 15 | 0 | X | -5.04 |
| Daniel Bard | 59.3 | 1.82 | 0 | 57 | X | 3.10 |
| Jonathan Papelbon | 54.7 | 2.96 | 0 | 53 | X | 1.40 |
| Scott Atchison | 44.7 | 3.83 | 1 | 28 | X | 0.24 |
| Manny Delcarmen | 44.0 | 4.70 | 0 | 48 | X | -0.66 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.35 |
| Felix Doubront | 23.3 | 3.86 | 3 | 7 | X | 0.11 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 10.3 | 2.61 | 0 | 19 | X | 0.35 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.03 |
| Michael Bowden | 6.0 | 7.50 | 0 | 6 | X | -0.48 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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