| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 557 | 69 | 40 | 0.272 | 0.332 | -1.35 | SS-2B |
| Adrian Beltre | 495 | 63 | 84 | 0.325 | 0.366 | 4.06 | 3B |
| David Ortiz | 456 | 67 | 78 | 0.268 | 0.375 | 4.75 | DH |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.60 | 1B |
| J.D. Drew | 422 | 58 | 56 | 0.258 | 0.348 | 2.28 | RF |
| Victor Martinez | 376 | 43 | 46 | 0.279 | 0.332 | 0.71 | CR-1B |
| Dustin Pedroia | 351 | 52 | 42 | 0.288 | 0.365 | 1.81 | 2B |
| Darnell McDonald | 285 | 29 | 31 | 0.274 | 0.330 | -0.25 | CF-RF-LF |
| Bill Hall | 284 | 36 | 38 | 0.243 | 0.313 | 1.25 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.04 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.38 | RF |
| Mike Lowell | 150 | 13 | 20 | 0.233 | 0.313 | 0.02 | 1B-DH |
| Daniel Nava | 114 | 14 | 17 | 0.273 | 0.368 | 0.64 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.05 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.35 | CF |
| Eric Patterson | 74 | 9 | 6 | 0.254 | 0.311 | -0.12 | LF |
| Jed Lowrie | 71 | 11 | 7 | 0.305 | 0.423 | 0.26 | 2B-SS |
| Ryan Kalish | 64 | 9 | 8 | 0.250 | 0.281 | 0.31 | CF-LF |
| Kevin Cash | 60 | 1 | 0 | 0.148 | 0.233 | -1.27 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.07 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 12 | 0 | 2 | 0.250 | 0.250 | -0.07 | X |
| Jarrod Saltalamacchia | 8 | 1 | 0 | 0.333 | 0.500 | -0.08 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Yamaico Navarro | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | SS |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 163.0 | 3.26 | 25 | 0 | X | 3.04 |
| John Lackey | 161.7 | 4.62 | 25 | 0 | X | -2.13 |
| Clay Buchholz | 133.3 | 2.36 | 21 | 0 | X | 5.27 |
| Tim Wakefield | 119.0 | 5.29 | 16 | 10 | X | -3.43 |
| Daisuke Matsuzaka | 110.0 | 4.17 | 18 | 0 | X | -0.30 |
| Josh Beckett | 82.3 | 6.67 | 14 | 0 | X | -5.02 |
| Daniel Bard | 54.7 | 1.98 | 0 | 54 | X | 2.66 |
| Jonathan Papelbon | 51.7 | 3.14 | 0 | 50 | X | 1.11 |
| Scott Atchison | 43.3 | 3.95 | 1 | 27 | X | 0.11 |
| Manny Delcarmen | 43.3 | 4.78 | 0 | 47 | X | -0.73 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.35 |
| Felix Doubront | 20.0 | 4.50 | 3 | 5 | X | -0.21 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Dustin Richardson | 10.3 | 2.61 | 0 | 19 | X | 0.35 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.03 |
| Michael Bowden | 6.0 | 7.50 | 0 | 6 | X | -0.48 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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