| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 537 | 66 | 39 | 0.268 | 0.328 | -1.31 | SS-2B |
| Adrian Beltre | 474 | 62 | 80 | 0.329 | 0.367 | 4.02 | 3B |
| David Ortiz | 439 | 63 | 77 | 0.261 | 0.364 | 4.62 | DH |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.60 | 1B |
| J.D. Drew | 411 | 57 | 56 | 0.264 | 0.353 | 2.42 | RF |
| Victor Martinez | 356 | 41 | 44 | 0.281 | 0.337 | 0.75 | CR-1B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.91 | 2B |
| Bill Hall | 273 | 35 | 37 | 0.246 | 0.319 | 1.29 | LF-2B |
| Darnell McDonald | 271 | 26 | 28 | 0.258 | 0.314 | -0.56 | CF-RF-LF |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.04 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.38 | RF |
| Mike Lowell | 131 | 12 | 20 | 0.248 | 0.321 | 0.35 | 1B-DH |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.69 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.05 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.35 | CF |
| Eric Patterson | 71 | 8 | 6 | 0.250 | 0.310 | -0.16 | LF |
| Jed Lowrie | 63 | 10 | 7 | 0.308 | 0.429 | 0.34 | 2B-SS |
| Kevin Cash | 60 | 1 | 0 | 0.148 | 0.233 | -1.27 | CR |
| Ryan Kalish | 47 | 8 | 4 | 0.326 | 0.362 | 0.18 | CF-LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.07 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Jarrod Saltalamacchia | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 161.0 | 2.80 | 24 | 0 | X | 4.77 |
| John Lackey | 154.7 | 4.54 | 24 | 0 | X | -1.71 |
| Clay Buchholz | 126.3 | 2.49 | 20 | 0 | X | 4.63 |
| Tim Wakefield | 115.0 | 5.48 | 16 | 8 | X | -3.79 |
| Daisuke Matsuzaka | 103.3 | 4.09 | 17 | 0 | X | -0.07 |
| Josh Beckett | 76.0 | 6.51 | 13 | 0 | X | -4.34 |
| Daniel Bard | 53.7 | 2.01 | 0 | 53 | X | 2.57 |
| Jonathan Papelbon | 50.7 | 3.20 | 0 | 49 | X | 1.02 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.40 |
| Manny Delcarmen | 41.7 | 4.32 | 0 | 44 | X | -0.25 |
| Scott Atchison | 40.7 | 3.98 | 1 | 25 | X | 0.08 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.34 |
| Felix Doubront | 19.0 | 4.74 | 3 | 4 | X | -0.30 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 10.3 | 1.74 | 0 | 18 | X | 0.56 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.03 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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