| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 532 | 66 | 38 | 0.268 | 0.327 | -1.33 | SS-2B |
| Adrian Beltre | 470 | 62 | 80 | 0.330 | 0.368 | 4.09 | 3B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.58 | 1B |
| David Ortiz | 434 | 63 | 77 | 0.262 | 0.366 | 4.71 | DH |
| J.D. Drew | 406 | 57 | 55 | 0.265 | 0.355 | 2.41 | RF |
| Victor Martinez | 351 | 41 | 44 | 0.284 | 0.339 | 0.85 | CR-1B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.89 | 2B |
| Darnell McDonald | 271 | 26 | 28 | 0.258 | 0.314 | -0.57 | CF-RF-LF |
| Bill Hall | 269 | 35 | 36 | 0.242 | 0.316 | 1.26 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.05 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.37 | RF |
| Mike Lowell | 127 | 11 | 20 | 0.248 | 0.323 | 0.33 | 1B-DH |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.69 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.05 | CR |
| Jacoby Ellsbury | 84 | 10 | 5 | 0.190 | 0.238 | -0.36 | CF |
| Eric Patterson | 67 | 8 | 6 | 0.250 | 0.313 | -0.07 | LF |
| Jed Lowrie | 63 | 10 | 7 | 0.308 | 0.429 | 0.33 | 2B-SS |
| Kevin Cash | 60 | 1 | 0 | 0.148 | 0.233 | -1.28 | CR |
| Ryan Kalish | 43 | 6 | 4 | 0.300 | 0.326 | 0.06 | CF-LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.07 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Jarrod Saltalamacchia | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 154.7 | 4.54 | 24 | 0 | X | -1.69 |
| Jon Lester | 153.0 | 2.94 | 23 | 0 | X | 4.03 |
| Clay Buchholz | 126.3 | 2.49 | 20 | 0 | X | 4.65 |
| Tim Wakefield | 115.0 | 5.48 | 16 | 8 | X | -3.78 |
| Daisuke Matsuzaka | 103.3 | 4.09 | 17 | 0 | X | -0.05 |
| Josh Beckett | 76.0 | 6.51 | 13 | 0 | X | -4.33 |
| Daniel Bard | 53.7 | 2.01 | 0 | 53 | X | 2.58 |
| Jonathan Papelbon | 50.7 | 3.20 | 0 | 49 | X | 1.03 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.39 |
| Manny Delcarmen | 41.7 | 4.32 | 0 | 44 | X | -0.24 |
| Scott Atchison | 40.3 | 3.79 | 1 | 24 | X | 0.26 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.34 |
| Felix Doubront | 18.3 | 4.91 | 3 | 3 | X | -0.36 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 10.3 | 1.74 | 0 | 18 | X | 0.56 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.03 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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