| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 516 | 65 | 37 | 0.273 | 0.333 | -1.23 | SS-2B |
| Adrian Beltre | 452 | 59 | 75 | 0.333 | 0.369 | 3.61 | 3B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| David Ortiz | 414 | 59 | 73 | 0.259 | 0.367 | 4.28 | DH |
| J.D. Drew | 388 | 52 | 51 | 0.260 | 0.351 | 1.84 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Victor Martinez | 330 | 39 | 40 | 0.282 | 0.339 | 0.66 | CR-1B |
| Darnell McDonald | 264 | 25 | 27 | 0.253 | 0.311 | -0.65 | CF-RF-LF |
| Bill Hall | 256 | 33 | 32 | 0.242 | 0.320 | 0.90 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Mike Lowell | 113 | 8 | 17 | 0.216 | 0.292 | 0.01 | 1B-DH |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.67 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Jacoby Ellsbury | 68 | 8 | 4 | 0.190 | 0.250 | -0.31 | CF |
| Eric Patterson | 65 | 8 | 6 | 0.224 | 0.292 | -0.03 | LF |
| Kevin Cash | 60 | 1 | 0 | 0.148 | 0.233 | -1.28 | CR |
| Jed Lowrie | 50 | 6 | 3 | 0.286 | 0.400 | -0.21 | 2B-SS |
| Ryan Kalish | 32 | 3 | 4 | 0.345 | 0.375 | -0.01 | CF-LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 153.0 | 2.94 | 23 | 0 | X | 4.07 |
| John Lackey | 146.7 | 4.60 | 23 | 0 | X | -1.78 |
| Clay Buchholz | 118.3 | 2.66 | 19 | 0 | X | 3.92 |
| Tim Wakefield | 115.0 | 5.40 | 16 | 7 | X | -3.54 |
| Daisuke Matsuzaka | 97.7 | 3.96 | 16 | 0 | X | 0.27 |
| Josh Beckett | 71.0 | 6.21 | 12 | 0 | X | -3.53 |
| Daniel Bard | 52.0 | 1.90 | 0 | 51 | X | 2.64 |
| Jonathan Papelbon | 48.3 | 2.79 | 0 | 46 | X | 1.45 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.38 |
| Scott Atchison | 39.7 | 3.86 | 1 | 23 | X | 0.21 |
| Manny Delcarmen | 39.7 | 4.54 | 0 | 42 | X | -0.42 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.33 |
| Felix Doubront | 16.3 | 3.86 | 3 | 1 | X | 0.09 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 9.0 | 2.00 | 0 | 16 | X | 0.44 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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