| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 511 | 65 | 37 | 0.275 | 0.335 | -1.12 | SS-2B |
| Adrian Beltre | 448 | 59 | 75 | 0.336 | 0.373 | 3.70 | 3B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.53 | 1B |
| David Ortiz | 410 | 59 | 73 | 0.259 | 0.368 | 4.37 | DH |
| J.D. Drew | 384 | 52 | 50 | 0.259 | 0.349 | 1.82 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Victor Martinez | 326 | 39 | 40 | 0.283 | 0.340 | 0.75 | CR-1B |
| Darnell McDonald | 264 | 25 | 27 | 0.253 | 0.311 | -0.65 | CF-RF-LF |
| Bill Hall | 252 | 32 | 31 | 0.242 | 0.321 | 0.78 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Mike Lowell | 109 | 8 | 17 | 0.224 | 0.303 | 0.10 | 1B-DH |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.67 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.03 | CR |
| Eric Patterson | 65 | 8 | 6 | 0.224 | 0.292 | -0.03 | LF |
| Jacoby Ellsbury | 64 | 8 | 4 | 0.180 | 0.219 | -0.22 | CF |
| Kevin Cash | 60 | 1 | 0 | 0.148 | 0.233 | -1.28 | CR |
| Jed Lowrie | 50 | 6 | 3 | 0.286 | 0.400 | -0.21 | 2B-SS |
| Ryan Kalish | 28 | 2 | 4 | 0.360 | 0.393 | -0.02 | CF-LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 146.7 | 4.60 | 23 | 0 | X | -1.78 |
| Jon Lester | 146.7 | 3.07 | 22 | 0 | X | 3.47 |
| Clay Buchholz | 118.3 | 2.66 | 19 | 0 | X | 3.92 |
| Tim Wakefield | 115.0 | 5.40 | 16 | 7 | X | -3.53 |
| Daisuke Matsuzaka | 97.7 | 3.96 | 16 | 0 | X | 0.28 |
| Josh Beckett | 71.0 | 6.21 | 12 | 0 | X | -3.53 |
| Daniel Bard | 50.7 | 1.78 | 0 | 50 | X | 2.73 |
| Jonathan Papelbon | 47.0 | 2.87 | 0 | 45 | X | 1.33 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.38 |
| Scott Atchison | 39.7 | 3.86 | 1 | 23 | X | 0.21 |
| Manny Delcarmen | 39.7 | 4.54 | 0 | 42 | X | -0.42 |
| Hideki Okajima | 32.3 | 5.85 | 0 | 40 | X | -1.33 |
| Felix Doubront | 16.3 | 3.86 | 3 | 1 | X | 0.09 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 9.0 | 2.00 | 0 | 16 | X | 0.44 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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