| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 493 | 64 | 35 | 0.279 | 0.339 | -1.00 | SS-2B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.54 | 1B |
| Adrian Beltre | 431 | 55 | 71 | 0.337 | 0.374 | 3.27 | 3B |
| David Ortiz | 393 | 57 | 72 | 0.261 | 0.372 | 4.46 | DH |
| J.D. Drew | 369 | 51 | 48 | 0.263 | 0.350 | 1.86 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.86 | 2B |
| Victor Martinez | 309 | 37 | 39 | 0.285 | 0.343 | 0.84 | CR-1B |
| Darnell McDonald | 261 | 25 | 27 | 0.257 | 0.314 | -0.57 | CF-RF-LF |
| Bill Hall | 242 | 31 | 30 | 0.239 | 0.322 | 0.81 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.07 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.35 | RF |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.68 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 95 | 6 | 15 | 0.214 | 0.305 | 0.01 | 1B-DH |
| Eric Patterson | 65 | 8 | 6 | 0.224 | 0.292 | -0.03 | LF |
| Kevin Cash | 58 | 1 | 0 | 0.154 | 0.241 | -1.24 | CR |
| Jacoby Ellsbury | 50 | 7 | 3 | 0.224 | 0.240 | -0.11 | CF |
| Jed Lowrie | 42 | 5 | 3 | 0.278 | 0.381 | -0.13 | 2B-SS |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Ryan Kalish | 17 | 1 | 2 | 0.500 | 0.529 | -0.08 | CF-LF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 146.7 | 3.07 | 22 | 0 | X | 3.48 |
| John Lackey | 140.7 | 4.48 | 22 | 0 | X | -1.29 |
| Tim Wakefield | 112.0 | 5.54 | 16 | 6 | X | -3.82 |
| Clay Buchholz | 111.0 | 2.59 | 18 | 0 | X | 3.86 |
| Daisuke Matsuzaka | 89.7 | 4.22 | 15 | 0 | X | -0.27 |
| Josh Beckett | 66.3 | 5.70 | 11 | 0 | X | -2.50 |
| Daniel Bard | 50.0 | 1.80 | 0 | 49 | X | 2.67 |
| Jonathan Papelbon | 45.3 | 2.98 | 0 | 43 | X | 1.17 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.38 |
| Scott Atchison | 39.7 | 3.86 | 1 | 23 | X | 0.21 |
| Manny Delcarmen | 38.3 | 4.70 | 0 | 40 | X | -0.55 |
| Hideki Okajima | 32.0 | 5.62 | 0 | 39 | X | -1.15 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | -0.01 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Dustin Richardson | 9.0 | 2.00 | 0 | 16 | X | 0.44 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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