| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 485 | 64 | 35 | 0.284 | 0.344 | -0.78 | SS-2B |
| Kevin Youkilis | 435 | 77 | 62 | 0.307 | 0.411 | 4.57 | 1B |
| Adrian Beltre | 423 | 54 | 71 | 0.336 | 0.374 | 3.38 | 3B |
| David Ortiz | 385 | 56 | 71 | 0.261 | 0.371 | 4.46 | DH |
| J.D. Drew | 365 | 51 | 48 | 0.266 | 0.353 | 1.98 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.88 | 2B |
| Victor Martinez | 301 | 37 | 39 | 0.284 | 0.339 | 1.04 | CR-1B |
| Darnell McDonald | 257 | 25 | 27 | 0.260 | 0.315 | -0.46 | CF-RF-LF |
| Bill Hall | 237 | 30 | 29 | 0.236 | 0.321 | 0.73 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.05 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.36 | RF |
| Daniel Nava | 107 | 14 | 16 | 0.290 | 0.383 | 0.68 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.21 | 1B-DH |
| Eric Patterson | 65 | 8 | 6 | 0.224 | 0.292 | -0.03 | LF |
| Kevin Cash | 54 | 1 | 0 | 0.143 | 0.222 | -1.14 | CR |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Jed Lowrie | 34 | 5 | 3 | 0.310 | 0.412 | 0.06 | 2B-SS |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.07 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Ryan Kalish | 12 | 1 | 2 | 0.500 | 0.500 | 0.04 | CF-LF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 141.7 | 3.05 | 21 | 0 | X | 3.42 |
| John Lackey | 140.7 | 4.48 | 22 | 0 | X | -1.30 |
| Tim Wakefield | 112.0 | 5.54 | 16 | 6 | X | -3.82 |
| Clay Buchholz | 111.0 | 2.59 | 18 | 0 | X | 3.86 |
| Daisuke Matsuzaka | 89.7 | 4.22 | 15 | 0 | X | -0.28 |
| Josh Beckett | 58.3 | 6.33 | 10 | 0 | X | -3.05 |
| Daniel Bard | 50.0 | 1.80 | 0 | 49 | X | 2.66 |
| Jonathan Papelbon | 44.3 | 3.05 | 0 | 42 | X | 1.07 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.38 |
| Scott Atchison | 37.7 | 4.06 | 1 | 22 | X | 0.02 |
| Manny Delcarmen | 37.3 | 4.82 | 0 | 39 | X | -0.64 |
| Hideki Okajima | 32.0 | 5.62 | 0 | 39 | X | -1.15 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | -0.01 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Dustin Richardson | 8.0 | 2.25 | 0 | 15 | X | 0.34 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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