| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 475 | 64 | 35 | 0.282 | 0.343 | -0.55 | SS-2B |
| Kevin Youkilis | 430 | 76 | 62 | 0.308 | 0.414 | 4.58 | 1B |
| Adrian Beltre | 415 | 51 | 65 | 0.332 | 0.371 | 2.61 | 3B |
| David Ortiz | 377 | 53 | 71 | 0.257 | 0.369 | 4.33 | DH |
| J.D. Drew | 356 | 51 | 48 | 0.269 | 0.357 | 2.19 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.88 | 2B |
| Victor Martinez | 293 | 37 | 39 | 0.292 | 0.348 | 1.23 | CR-1B |
| Darnell McDonald | 257 | 25 | 27 | 0.260 | 0.315 | -0.46 | CF-RF-LF |
| Bill Hall | 233 | 30 | 29 | 0.235 | 0.322 | 0.82 | LF-2B |
| Mike Cameron | 180 | 24 | 15 | 0.259 | 0.328 | -0.05 | CF |
| Jeremy Hermida | 171 | 14 | 27 | 0.203 | 0.257 | 0.36 | RF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Daniel Nava | 105 | 14 | 16 | 0.286 | 0.381 | 0.73 | LF |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.21 | 1B-DH |
| Eric Patterson | 59 | 8 | 5 | 0.226 | 0.288 | 0.01 | LF |
| Kevin Cash | 52 | 1 | 0 | 0.149 | 0.231 | -1.09 | CR |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Jed Lowrie | 28 | 3 | 3 | 0.250 | 0.357 | -0.02 | 2B-SS |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.07 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Dusty Brown | 11 | 0 | 0 | 0.182 | 0.182 | -0.25 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Ryan Kalish | 4 | 1 | 1 | 0.500 | 0.500 | 0.12 | CF-LF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 141.7 | 3.05 | 21 | 0 | X | 3.43 |
| John Lackey | 135.3 | 4.26 | 21 | 0 | X | -0.53 |
| Tim Wakefield | 110.0 | 5.65 | 16 | 5 | X | -4.00 |
| Clay Buchholz | 103.0 | 2.71 | 17 | 0 | X | 3.31 |
| Daisuke Matsuzaka | 89.7 | 4.22 | 15 | 0 | X | -0.27 |
| Josh Beckett | 58.3 | 6.33 | 10 | 0 | X | -3.05 |
| Daniel Bard | 49.0 | 1.84 | 0 | 48 | X | 2.57 |
| Jonathan Papelbon | 43.3 | 2.91 | 0 | 41 | X | 1.19 |
| Ramon S. Ramirez | 42.3 | 4.46 | 0 | 44 | X | -0.37 |
| Scott Atchison | 37.7 | 4.06 | 1 | 22 | X | 0.02 |
| Manny Delcarmen | 37.0 | 4.86 | 0 | 38 | X | -0.67 |
| Hideki Okajima | 32.0 | 5.62 | 0 | 39 | X | -1.15 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | -0.01 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Dustin Richardson | 7.7 | 2.35 | 0 | 14 | X | 0.31 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
_