| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 445 | 58 | 30 | 0.276 | 0.337 | -1.06 | SS-2B |
| Kevin Youkilis | 401 | 72 | 60 | 0.304 | 0.406 | 4.58 | 1B |
| Adrian Beltre | 388 | 48 | 62 | 0.333 | 0.374 | 2.57 | 3B |
| David Ortiz | 349 | 48 | 61 | 0.252 | 0.367 | 3.37 | DH |
| J.D. Drew | 342 | 50 | 46 | 0.266 | 0.351 | 2.17 | RF |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.63 | CR-1B |
| Darnell McDonald | 242 | 23 | 26 | 0.256 | 0.306 | -0.45 | CF-RF-LF |
| Bill Hall | 221 | 28 | 28 | 0.232 | 0.317 | 0.77 | LF-2B |
| Mike Cameron | 163 | 23 | 15 | 0.281 | 0.350 | 0.22 | CF |
| Jeremy Hermida | 153 | 13 | 27 | 0.225 | 0.275 | 0.66 | RF |
| Daniel Nava | 105 | 14 | 16 | 0.286 | 0.381 | 0.72 | LF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Kevin Cash | 52 | 1 | 0 | 0.149 | 0.231 | -1.10 | CR |
| Eric Patterson | 48 | 7 | 5 | 0.205 | 0.271 | 0.15 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Jed Lowrie | 13 | 1 | 1 | 0.182 | 0.308 | -0.09 | 2B-SS |
| Dusty Brown | 8 | 0 | 0 | 0.125 | 0.125 | -0.19 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 135.7 | 2.92 | 20 | 0 | X | 3.69 |
| John Lackey | 128.0 | 4.36 | 20 | 0 | X | -0.82 |
| Tim Wakefield | 108.0 | 5.58 | 16 | 4 | X | -3.78 |
| Clay Buchholz | 96.0 | 2.81 | 16 | 0 | X | 2.85 |
| Daisuke Matsuzaka | 77.7 | 4.29 | 13 | 0 | X | -0.37 |
| Josh Beckett | 51.3 | 6.66 | 9 | 0 | X | -3.09 |
| Daniel Bard | 47.3 | 1.71 | 0 | 46 | X | 2.62 |
| Jonathan Papelbon | 41.0 | 3.07 | 0 | 39 | X | 0.97 |
| Ramon S. Ramirez | 40.0 | 4.72 | 0 | 41 | X | -0.60 |
| Manny Delcarmen | 36.0 | 5.00 | 0 | 37 | X | -0.77 |
| Scott Atchison | 35.7 | 3.79 | 1 | 20 | X | 0.25 |
| Hideki Okajima | 30.3 | 5.34 | 0 | 37 | X | -0.89 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | -0.01 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Dustin Richardson | 7.0 | 2.57 | 0 | 13 | X | 0.25 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Michael Bowden | 2.3 | 0.00 | 0 | 3 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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