| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 430 | 56 | 29 | 0.279 | 0.342 | -1.07 | SS-2B |
| Kevin Youkilis | 383 | 69 | 60 | 0.297 | 0.405 | 4.64 | 1B |
| Adrian Beltre | 370 | 46 | 58 | 0.334 | 0.373 | 2.32 | 3B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.81 | 2B |
| David Ortiz | 331 | 47 | 59 | 0.253 | 0.372 | 3.43 | DH |
| J.D. Drew | 324 | 49 | 44 | 0.270 | 0.352 | 2.23 | RF |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.60 | CR-1B |
| Darnell McDonald | 233 | 23 | 26 | 0.266 | 0.313 | -0.27 | CF-RF-LF |
| Bill Hall | 210 | 25 | 25 | 0.230 | 0.319 | 0.37 | LF-2B |
| Mike Cameron | 149 | 21 | 15 | 0.284 | 0.349 | 0.31 | CF |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.73 | RF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.02 | CR |
| Daniel Nava | 104 | 14 | 16 | 0.289 | 0.385 | 0.73 | LF |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.23 | 1B-DH |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Kevin Cash | 41 | 1 | 0 | 0.139 | 0.244 | -0.85 | CR |
| Eric Patterson | 40 | 7 | 3 | 0.216 | 0.275 | 0.12 | LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 7 | 0 | 0 | 0.000 | 0.000 | -0.16 | X |
| Dusty Brown | 4 | 0 | 0 | 0.250 | 0.250 | -0.09 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 128.0 | 2.81 | 19 | 0 | X | 3.87 |
| John Lackey | 120.0 | 4.65 | 19 | 0 | X | -1.51 |
| Tim Wakefield | 108.0 | 5.58 | 16 | 4 | X | -3.71 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.57 |
| Daisuke Matsuzaka | 77.7 | 4.29 | 13 | 0 | X | -0.32 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.39 |
| Daniel Bard | 45.3 | 1.79 | 0 | 44 | X | 2.46 |
| Ramon S. Ramirez | 39.0 | 4.85 | 0 | 40 | X | -0.67 |
| Jonathan Papelbon | 39.0 | 3.23 | 0 | 37 | X | 0.80 |
| Manny Delcarmen | 35.7 | 4.29 | 0 | 35 | X | -0.15 |
| Scott Atchison | 31.7 | 4.26 | 1 | 18 | X | -0.11 |
| Hideki Okajima | 28.3 | 5.72 | 0 | 36 | X | -1.06 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | 0.00 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Dustin Richardson | 7.0 | 2.57 | 0 | 13 | X | 0.25 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Michael Bowden | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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