| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 420 | 54 | 28 | 0.277 | 0.338 | -1.12 | SS-2B |
| Kevin Youkilis | 374 | 69 | 59 | 0.301 | 0.409 | 4.78 | 1B |
| Adrian Beltre | 361 | 45 | 57 | 0.328 | 0.368 | 2.35 | 3B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.84 | 2B |
| David Ortiz | 322 | 47 | 58 | 0.256 | 0.376 | 3.57 | DH |
| J.D. Drew | 315 | 49 | 44 | 0.274 | 0.356 | 2.47 | RF |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.62 | CR-1B |
| Darnell McDonald | 224 | 23 | 25 | 0.266 | 0.317 | -0.15 | CF-RF-LF |
| Bill Hall | 204 | 24 | 25 | 0.230 | 0.319 | 0.42 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 144 | 20 | 15 | 0.282 | 0.340 | 0.34 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.03 | CR |
| Daniel Nava | 100 | 14 | 16 | 0.291 | 0.390 | 0.83 | LF |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Eric Patterson | 37 | 6 | 3 | 0.206 | 0.270 | 0.09 | LF |
| Kevin Cash | 34 | 1 | 0 | 0.100 | 0.206 | -0.68 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 6 | 0 | 0 | 0.000 | 0.000 | -0.14 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Dusty Brown | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 128.0 | 2.81 | 19 | 0 | X | 3.83 |
| John Lackey | 120.0 | 4.65 | 19 | 0 | X | -1.55 |
| Tim Wakefield | 102.0 | 5.65 | 15 | 4 | X | -3.69 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.54 |
| Daisuke Matsuzaka | 71.0 | 4.56 | 12 | 0 | X | -0.78 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 43.7 | 1.85 | 0 | 42 | X | 2.28 |
| Jonathan Papelbon | 38.0 | 3.32 | 0 | 36 | X | 0.69 |
| Ramon S. Ramirez | 37.7 | 4.78 | 0 | 39 | X | -0.60 |
| Manny Delcarmen | 34.3 | 4.46 | 0 | 34 | X | -0.29 |
| Scott Atchison | 31.7 | 4.26 | 1 | 18 | X | -0.12 |
| Hideki Okajima | 28.0 | 5.79 | 0 | 35 | X | -1.10 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | 0.00 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Dustin Richardson | 6.7 | 2.70 | 0 | 12 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Michael Bowden | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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