| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 415 | 54 | 28 | 0.278 | 0.340 | -0.99 | SS-2B |
| Kevin Youkilis | 370 | 68 | 59 | 0.297 | 0.405 | 4.77 | 1B |
| Adrian Beltre | 357 | 45 | 56 | 0.329 | 0.370 | 2.35 | 3B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| David Ortiz | 318 | 47 | 58 | 0.260 | 0.381 | 3.67 | DH |
| J.D. Drew | 313 | 49 | 44 | 0.275 | 0.355 | 2.52 | RF |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.63 | CR-1B |
| Darnell McDonald | 220 | 23 | 25 | 0.270 | 0.318 | -0.05 | CF-RF-LF |
| Bill Hall | 200 | 24 | 25 | 0.234 | 0.320 | 0.52 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 140 | 19 | 14 | 0.283 | 0.343 | 0.23 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Daniel Nava | 97 | 14 | 16 | 0.294 | 0.381 | 0.91 | LF |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Eric Patterson | 37 | 6 | 3 | 0.206 | 0.270 | 0.09 | LF |
| Kevin Cash | 33 | 1 | 0 | 0.103 | 0.212 | -0.66 | CR |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Ryan Shealy | 6 | 0 | 0 | 0.000 | 0.000 | -0.14 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Dusty Brown | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 120.0 | 4.65 | 19 | 0 | X | -1.56 |
| Jon Lester | 120.0 | 2.77 | 18 | 0 | X | 3.69 |
| Tim Wakefield | 102.0 | 5.65 | 15 | 4 | X | -3.70 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.54 |
| Daisuke Matsuzaka | 71.0 | 4.56 | 12 | 0 | X | -0.78 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 43.7 | 1.85 | 0 | 42 | X | 2.28 |
| Jonathan Papelbon | 38.0 | 3.32 | 0 | 36 | X | 0.69 |
| Ramon S. Ramirez | 37.7 | 4.78 | 0 | 39 | X | -0.60 |
| Manny Delcarmen | 34.3 | 4.46 | 0 | 34 | X | -0.29 |
| Scott Atchison | 31.7 | 4.26 | 1 | 18 | X | -0.13 |
| Hideki Okajima | 28.0 | 5.79 | 0 | 35 | X | -1.11 |
| Felix Doubront | 15.3 | 4.11 | 3 | 0 | X | -0.01 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Robert Manuel | 7.0 | 3.86 | 0 | 5 | X | 0.04 |
| Dustin Richardson | 6.7 | 2.70 | 0 | 12 | X | 0.22 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Fernando Cabrera | 1.3 | 20.25 | 0 | 1 | X | -0.50 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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