| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 396 | 51 | 28 | 0.283 | 0.346 | -0.87 | SS-2B |
| Kevin Youkilis | 353 | 67 | 57 | 0.293 | 0.408 | 4.85 | 1B |
| Adrian Beltre | 347 | 44 | 55 | 0.332 | 0.372 | 2.37 | 3B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| David Ortiz | 301 | 45 | 56 | 0.262 | 0.382 | 3.64 | DH |
| J.D. Drew | 297 | 47 | 41 | 0.279 | 0.364 | 2.37 | RF |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.63 | CR-1B |
| Darnell McDonald | 211 | 21 | 23 | 0.271 | 0.322 | -0.26 | CF-RF-LF |
| Bill Hall | 184 | 23 | 24 | 0.239 | 0.332 | 0.68 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 132 | 19 | 14 | 0.283 | 0.341 | 0.41 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Daniel Nava | 86 | 14 | 16 | 0.312 | 0.384 | 1.16 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Eric Patterson | 27 | 6 | 3 | 0.280 | 0.333 | 0.32 | LF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Kevin Cash | 22 | 1 | 0 | 0.105 | 0.227 | -0.40 | CR |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Gustavo Molina | 7 | 1 | 0 | 0.143 | 0.143 | -0.06 | X |
| Niuman Romero | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Ryan Shealy | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 120.0 | 2.77 | 18 | 0 | X | 3.75 |
| John Lackey | 113.0 | 4.78 | 18 | 0 | X | -1.76 |
| Tim Wakefield | 100.0 | 5.22 | 14 | 4 | X | -2.58 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.58 |
| Daisuke Matsuzaka | 65.0 | 4.71 | 11 | 0 | X | -0.90 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.39 |
| Daniel Bard | 40.7 | 1.99 | 0 | 40 | X | 2.01 |
| Ramon S. Ramirez | 35.7 | 4.79 | 0 | 37 | X | -0.57 |
| Jonathan Papelbon | 35.0 | 3.60 | 0 | 34 | X | 0.42 |
| Manny Delcarmen | 33.3 | 4.59 | 0 | 33 | X | -0.37 |
| Scott Atchison | 28.7 | 4.71 | 1 | 17 | X | -0.40 |
| Hideki Okajima | 27.0 | 6.00 | 0 | 34 | X | -1.19 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Felix Doubront | 10.7 | 4.22 | 2 | 0 | X | -0.03 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Dustin Richardson | 5.3 | 3.38 | 0 | 10 | X | 0.09 |
| Robert Manuel | 4.3 | 6.23 | 0 | 4 | X | -0.21 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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