| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 378 | 49 | 25 | 0.279 | 0.341 | -1.00 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.83 | 2B |
| Kevin Youkilis | 339 | 66 | 55 | 0.299 | 0.416 | 4.84 | 1B |
| Adrian Beltre | 329 | 41 | 54 | 0.340 | 0.377 | 2.34 | 3B |
| J.D. Drew | 284 | 44 | 40 | 0.280 | 0.366 | 2.23 | RF |
| David Ortiz | 280 | 44 | 54 | 0.261 | 0.371 | 3.79 | DH |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.61 | CR-1B |
| Darnell McDonald | 199 | 19 | 21 | 0.260 | 0.312 | -0.42 | CF-RF-LF |
| Bill Hall | 167 | 21 | 20 | 0.234 | 0.329 | 0.43 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.74 | RF |
| Mike Cameron | 119 | 14 | 9 | 0.255 | 0.311 | -0.35 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.03 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Daniel Nava | 71 | 10 | 13 | 0.302 | 0.380 | 0.77 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Eric Patterson | 17 | 6 | 2 | 0.333 | 0.412 | 0.45 | LF |
| Kevin Cash | 10 | 0 | 0 | 0.100 | 0.100 | -0.23 | CR |
| Gustavo Molina | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 114.0 | 2.76 | 17 | 0 | X | 3.53 |
| John Lackey | 108.3 | 4.40 | 17 | 0 | X | -0.79 |
| Tim Wakefield | 94.3 | 4.96 | 13 | 4 | X | -1.92 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.53 |
| Daisuke Matsuzaka | 65.0 | 4.71 | 11 | 0 | X | -0.94 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 40.7 | 1.99 | 0 | 40 | X | 1.99 |
| Jonathan Papelbon | 34.0 | 3.71 | 0 | 33 | X | 0.30 |
| Ramon S. Ramirez | 33.7 | 4.81 | 0 | 35 | X | -0.57 |
| Manny Delcarmen | 33.3 | 4.59 | 0 | 33 | X | -0.39 |
| Scott Atchison | 26.3 | 5.13 | 1 | 15 | X | -0.64 |
| Hideki Okajima | 26.3 | 5.81 | 0 | 33 | X | -1.06 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Dustin Richardson | 3.7 | 2.45 | 0 | 7 | X | 0.14 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Robert Manuel | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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