| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 373 | 49 | 25 | 0.280 | 0.343 | -0.87 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.84 | 2B |
| Kevin Youkilis | 334 | 65 | 54 | 0.299 | 0.416 | 4.76 | 1B |
| Adrian Beltre | 325 | 40 | 53 | 0.341 | 0.378 | 2.23 | 3B |
| J.D. Drew | 280 | 44 | 40 | 0.281 | 0.368 | 2.33 | RF |
| David Ortiz | 275 | 43 | 54 | 0.259 | 0.364 | 3.81 | DH |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.62 | CR-1B |
| Darnell McDonald | 199 | 19 | 21 | 0.260 | 0.312 | -0.41 | CF-RF-LF |
| Bill Hall | 163 | 21 | 19 | 0.227 | 0.325 | 0.42 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 115 | 14 | 9 | 0.264 | 0.322 | -0.25 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.03 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Daniel Nava | 70 | 10 | 13 | 0.306 | 0.386 | 0.79 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Eric Patterson | 12 | 4 | 0 | 0.200 | 0.333 | 0.14 | LF |
| Kevin Cash | 7 | 0 | 0 | 0.143 | 0.143 | -0.16 | CR |
| Gustavo Molina | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 114.0 | 2.76 | 17 | 0 | X | 3.49 |
| John Lackey | 108.3 | 4.40 | 17 | 0 | X | -0.82 |
| Tim Wakefield | 94.3 | 4.96 | 13 | 4 | X | -1.95 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.50 |
| Daisuke Matsuzaka | 60.0 | 4.50 | 10 | 0 | X | -0.59 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daniel Bard | 39.7 | 2.04 | 0 | 39 | X | 1.88 |
| Jonathan Papelbon | 34.0 | 3.71 | 0 | 33 | X | 0.29 |
| Manny Delcarmen | 33.3 | 4.59 | 0 | 33 | X | -0.40 |
| Ramon S. Ramirez | 32.3 | 4.73 | 0 | 34 | X | -0.49 |
| Scott Atchison | 26.3 | 5.13 | 1 | 15 | X | -0.64 |
| Hideki Okajima | 26.3 | 5.81 | 0 | 33 | X | -1.06 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Dustin Richardson | 3.0 | 3.00 | 0 | 6 | X | 0.08 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Robert Manuel | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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