| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 369 | 49 | 25 | 0.284 | 0.347 | -0.76 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Kevin Youkilis | 330 | 64 | 53 | 0.299 | 0.415 | 4.65 | 1B |
| Adrian Beltre | 321 | 40 | 53 | 0.341 | 0.377 | 2.34 | 3B |
| J.D. Drew | 276 | 44 | 40 | 0.286 | 0.373 | 2.44 | RF |
| David Ortiz | 271 | 43 | 54 | 0.263 | 0.369 | 3.92 | DH |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.63 | CR-1B |
| Darnell McDonald | 195 | 19 | 21 | 0.266 | 0.318 | -0.31 | CF-RF-LF |
| Bill Hall | 159 | 21 | 19 | 0.225 | 0.321 | 0.52 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 115 | 14 | 9 | 0.264 | 0.322 | -0.24 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.21 | 1B-DH |
| Daniel Nava | 66 | 10 | 13 | 0.317 | 0.379 | 0.89 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Eric Patterson | 12 | 4 | 0 | 0.200 | 0.333 | 0.14 | LF |
| Kevin Cash | 7 | 0 | 0 | 0.143 | 0.143 | -0.16 | CR |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Gustavo Molina | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 114.0 | 2.76 | 17 | 0 | X | 3.49 |
| John Lackey | 101.0 | 4.46 | 16 | 0 | X | -0.90 |
| Tim Wakefield | 94.3 | 4.96 | 13 | 4 | X | -1.95 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.50 |
| Daisuke Matsuzaka | 60.0 | 4.50 | 10 | 0 | X | -0.59 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daniel Bard | 39.7 | 2.04 | 0 | 39 | X | 1.88 |
| Jonathan Papelbon | 34.0 | 3.71 | 0 | 33 | X | 0.29 |
| Manny Delcarmen | 33.3 | 4.59 | 0 | 33 | X | -0.40 |
| Ramon S. Ramirez | 32.3 | 4.73 | 0 | 34 | X | -0.50 |
| Hideki Okajima | 26.3 | 5.81 | 0 | 33 | X | -1.07 |
| Scott Atchison | 25.3 | 4.62 | 1 | 14 | X | -0.32 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Dustin Richardson | 2.3 | 3.86 | 0 | 5 | X | 0.01 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Robert Manuel | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
_