| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 364 | 49 | 25 | 0.285 | 0.349 | -0.64 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.87 | 2B |
| Kevin Youkilis | 325 | 62 | 50 | 0.297 | 0.415 | 4.25 | 1B |
| Adrian Beltre | 317 | 40 | 53 | 0.346 | 0.382 | 2.44 | 3B |
| J.D. Drew | 272 | 43 | 38 | 0.277 | 0.364 | 2.22 | RF |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.64 | CR-1B |
| David Ortiz | 266 | 41 | 53 | 0.254 | 0.361 | 3.73 | DH |
| Darnell McDonald | 195 | 19 | 21 | 0.266 | 0.318 | -0.30 | CF-RF-LF |
| Bill Hall | 159 | 21 | 19 | 0.225 | 0.321 | 0.53 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.76 | RF |
| Mike Cameron | 111 | 13 | 8 | 0.265 | 0.324 | -0.36 | CF |
| Jason Varitek | 105 | 17 | 16 | 0.263 | 0.324 | 1.04 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.21 | 1B-DH |
| Daniel Nava | 62 | 9 | 12 | 0.304 | 0.371 | 0.77 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Eric Patterson | 7 | 2 | 0 | 0.167 | 0.286 | 0.05 | LF |
| Kevin Cash | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | CR |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Gustavo Molina | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 107.0 | 2.86 | 16 | 0 | X | 3.02 |
| John Lackey | 101.0 | 4.46 | 16 | 0 | X | -0.91 |
| Tim Wakefield | 94.3 | 4.96 | 13 | 4 | X | -1.96 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.49 |
| Daisuke Matsuzaka | 60.0 | 4.50 | 10 | 0 | X | -0.60 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daniel Bard | 39.7 | 2.04 | 0 | 39 | X | 1.88 |
| Jonathan Papelbon | 34.0 | 3.71 | 0 | 33 | X | 0.29 |
| Manny Delcarmen | 33.3 | 4.59 | 0 | 33 | X | -0.40 |
| Ramon S. Ramirez | 31.3 | 4.88 | 0 | 33 | X | -0.59 |
| Hideki Okajima | 26.3 | 5.81 | 0 | 33 | X | -1.07 |
| Scott Atchison | 25.3 | 4.62 | 1 | 14 | X | -0.32 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.16 |
| Dustin Richardson | 2.3 | 3.86 | 0 | 5 | X | 0.01 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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