| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 321 | 45 | 37 | 0.277 | 0.352 | 1.16 | 2B |
| Marco Scutaro | 317 | 43 | 23 | 0.283 | 0.350 | -0.43 | SS-2B |
| Kevin Youkilis | 290 | 58 | 46 | 0.313 | 0.438 | 4.19 | 1B |
| Adrian Beltre | 279 | 31 | 48 | 0.337 | 0.373 | 1.82 | 3B |
| J.D. Drew | 259 | 40 | 36 | 0.276 | 0.359 | 1.97 | RF |
| Victor Martinez | 245 | 35 | 37 | 0.295 | 0.347 | 1.87 | CR-1B |
| David Ortiz | 234 | 36 | 45 | 0.263 | 0.368 | 3.07 | DH |
| Darnell McDonald | 164 | 17 | 18 | 0.276 | 0.323 | -0.13 | CF-RF-LF |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.74 | RF |
| Bill Hall | 134 | 18 | 16 | 0.239 | 0.328 | 0.46 | LF-2B |
| Mike Lowell | 90 | 5 | 13 | 0.215 | 0.311 | -0.20 | 1B-DH |
| Jason Varitek | 89 | 17 | 12 | 0.275 | 0.348 | 0.98 | CR |
| Mike Cameron | 84 | 10 | 2 | 0.267 | 0.345 | -0.69 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Daniel Nava | 27 | 5 | 7 | 0.360 | 0.407 | 0.63 | LF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 17 | 2 | 3 | 0.176 | 0.176 | 0.13 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 92.0 | 3.13 | 14 | 0 | X | 2.08 |
| John Lackey | 87.3 | 4.53 | 14 | 0 | X | -0.88 |
| Clay Buchholz | 84.3 | 2.67 | 13 | 0 | X | 2.82 |
| Tim Wakefield | 79.3 | 5.33 | 11 | 4 | X | -2.28 |
| Daisuke Matsuzaka | 49.0 | 4.59 | 8 | 0 | X | -0.56 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.40 |
| Daniel Bard | 35.3 | 2.29 | 0 | 34 | X | 1.49 |
| Manny Delcarmen | 32.0 | 2.25 | 0 | 29 | X | 1.38 |
| Jonathan Papelbon | 28.3 | 2.86 | 0 | 27 | X | 0.82 |
| Ramon S. Ramirez | 26.3 | 5.13 | 0 | 28 | X | -0.63 |
| Hideki Okajima | 23.3 | 4.24 | 0 | 29 | X | -0.08 |
| Scott Atchison | 20.0 | 4.05 | 1 | 10 | X | 0.02 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Dustin Richardson | 1.0 | 9.00 | 0 | 3 | X | -0.11 |
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