| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 306 | 42 | 35 | 0.271 | 0.346 | 0.98 | 2B |
| Marco Scutaro | 302 | 43 | 19 | 0.286 | 0.354 | -0.51 | SS-2B |
| Kevin Youkilis | 277 | 55 | 43 | 0.318 | 0.448 | 3.85 | 1B |
| Adrian Beltre | 266 | 28 | 45 | 0.336 | 0.368 | 1.49 | 3B |
| J.D. Drew | 254 | 39 | 35 | 0.277 | 0.362 | 1.87 | RF |
| Victor Martinez | 237 | 32 | 35 | 0.295 | 0.346 | 1.53 | CR-1B |
| David Ortiz | 220 | 33 | 41 | 0.259 | 0.355 | 2.66 | DH |
| Darnell McDonald | 152 | 15 | 16 | 0.281 | 0.329 | -0.28 | CF-RF-LF |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.74 | RF |
| Bill Hall | 130 | 18 | 16 | 0.230 | 0.323 | 0.55 | LF-2B |
| Mike Lowell | 90 | 5 | 13 | 0.215 | 0.311 | -0.20 | 1B-DH |
| Jason Varitek | 85 | 16 | 12 | 0.263 | 0.341 | 0.97 | CR |
| Mike Cameron | 80 | 9 | 2 | 0.254 | 0.338 | -0.70 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 17 | 2 | 3 | 0.176 | 0.176 | 0.13 | RF |
| Daniel Nava | 15 | 2 | 5 | 0.357 | 0.400 | 0.39 | LF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 92.0 | 3.13 | 14 | 0 | X | 2.09 |
| Clay Buchholz | 84.3 | 2.67 | 13 | 0 | X | 2.82 |
| John Lackey | 81.3 | 4.54 | 13 | 0 | X | -0.82 |
| Tim Wakefield | 73.0 | 5.42 | 10 | 4 | X | -2.25 |
| Daisuke Matsuzaka | 49.0 | 4.59 | 8 | 0 | X | -0.56 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.40 |
| Daniel Bard | 34.7 | 2.34 | 0 | 33 | X | 1.43 |
| Manny Delcarmen | 30.7 | 2.35 | 0 | 27 | X | 1.26 |
| Ramon S. Ramirez | 26.3 | 5.13 | 0 | 28 | X | -0.63 |
| Jonathan Papelbon | 26.3 | 2.73 | 0 | 25 | X | 0.84 |
| Hideki Okajima | 21.0 | 4.71 | 0 | 27 | X | -0.30 |
| Scott Atchison | 17.0 | 4.76 | 1 | 9 | X | -0.26 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Dustin Richardson | 0.7 | 0.00 | 0 | 1 | X | 0.06 |
_