| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 294 | 37 | 32 | 0.255 | 0.333 | 0.47 | 2B |
| Marco Scutaro | 293 | 42 | 19 | 0.284 | 0.355 | -0.35 | SS-2B |
| Kevin Youkilis | 269 | 54 | 40 | 0.316 | 0.450 | 3.67 | 1B |
| Adrian Beltre | 254 | 27 | 43 | 0.336 | 0.370 | 1.49 | 3B |
| J.D. Drew | 242 | 38 | 34 | 0.276 | 0.360 | 1.98 | RF |
| Victor Martinez | 225 | 32 | 34 | 0.301 | 0.351 | 1.74 | CR-1B |
| David Ortiz | 208 | 29 | 39 | 0.251 | 0.346 | 2.34 | DH |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.77 | RF |
| Darnell McDonald | 148 | 15 | 16 | 0.290 | 0.338 | -0.16 | CF-RF-LF |
| Bill Hall | 126 | 18 | 16 | 0.239 | 0.333 | 0.67 | LF-2B |
| Mike Lowell | 86 | 5 | 13 | 0.227 | 0.326 | -0.09 | 1B-DH |
| Jason Varitek | 85 | 16 | 12 | 0.263 | 0.341 | 0.98 | CR |
| Mike Cameron | 72 | 8 | 2 | 0.270 | 0.361 | -0.61 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Josh Reddick | 17 | 2 | 3 | 0.176 | 0.176 | 0.13 | RF |
| Daniel Nava | 4 | 1 | 4 | 0.500 | 0.500 | 0.43 | LF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 85.0 | 3.18 | 13 | 0 | X | 1.80 |
| John Lackey | 81.3 | 4.54 | 13 | 0 | X | -0.86 |
| Clay Buchholz | 78.7 | 2.52 | 12 | 0 | X | 2.87 |
| Tim Wakefield | 65.7 | 5.48 | 9 | 4 | X | -2.15 |
| Daisuke Matsuzaka | 49.0 | 4.59 | 8 | 0 | X | -0.58 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.42 |
| Daniel Bard | 32.7 | 2.48 | 0 | 31 | X | 1.22 |
| Manny Delcarmen | 30.0 | 2.40 | 0 | 26 | X | 1.18 |
| Jonathan Papelbon | 25.0 | 2.88 | 0 | 23 | X | 0.70 |
| Ramon S. Ramirez | 24.7 | 5.11 | 0 | 26 | X | -0.59 |
| Hideki Okajima | 20.3 | 4.87 | 0 | 26 | X | -0.37 |
| Scott Atchison | 17.0 | 4.76 | 1 | 9 | X | -0.27 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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