| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 289 | 37 | 31 | 0.251 | 0.329 | 0.45 | 2B |
| Marco Scutaro | 288 | 42 | 17 | 0.286 | 0.358 | -0.47 | SS-2B |
| Kevin Youkilis | 265 | 52 | 40 | 0.316 | 0.449 | 3.53 | 1B |
| Adrian Beltre | 249 | 26 | 43 | 0.333 | 0.365 | 1.48 | 3B |
| J.D. Drew | 237 | 36 | 32 | 0.267 | 0.350 | 1.66 | RF |
| Victor Martinez | 225 | 32 | 34 | 0.301 | 0.351 | 1.72 | CR-1B |
| David Ortiz | 203 | 29 | 39 | 0.247 | 0.345 | 2.44 | DH |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Darnell McDonald | 143 | 13 | 16 | 0.286 | 0.336 | -0.26 | CF-RF-LF |
| Bill Hall | 126 | 18 | 16 | 0.239 | 0.333 | 0.65 | LF-2B |
| Mike Lowell | 85 | 5 | 13 | 0.230 | 0.329 | -0.08 | 1B-DH |
| Jason Varitek | 80 | 14 | 12 | 0.264 | 0.338 | 0.88 | CR |
| Mike Cameron | 72 | 8 | 2 | 0.270 | 0.361 | -0.62 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 17 | 2 | 3 | 0.176 | 0.176 | 0.13 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 85.0 | 3.18 | 13 | 0 | X | 1.81 |
| John Lackey | 81.3 | 4.54 | 13 | 0 | X | -0.85 |
| Clay Buchholz | 78.7 | 2.52 | 12 | 0 | X | 2.88 |
| Tim Wakefield | 65.7 | 5.48 | 9 | 4 | X | -2.14 |
| Daisuke Matsuzaka | 49.0 | 4.59 | 8 | 0 | X | -0.58 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 32.7 | 2.48 | 0 | 31 | X | 1.23 |
| Manny Delcarmen | 28.0 | 2.57 | 0 | 25 | X | 0.99 |
| Jonathan Papelbon | 24.0 | 3.00 | 0 | 22 | X | 0.61 |
| Ramon S. Ramirez | 23.0 | 5.48 | 0 | 25 | X | -0.75 |
| Hideki Okajima | 19.0 | 5.21 | 0 | 25 | X | -0.50 |
| Scott Atchison | 14.0 | 4.50 | 0 | 9 | X | -0.13 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.10 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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