| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 245 | 33 | 27 | 0.252 | 0.327 | 0.60 | 2B |
| Marco Scutaro | 241 | 31 | 11 | 0.271 | 0.353 | -1.20 | SS-2B |
| Kevin Youkilis | 229 | 47 | 32 | 0.302 | 0.445 | 2.97 | 1B |
| Adrian Beltre | 213 | 22 | 37 | 0.335 | 0.366 | 1.24 | 3B |
| J.D. Drew | 212 | 33 | 30 | 0.269 | 0.344 | 1.68 | RF |
| Victor Martinez | 185 | 25 | 26 | 0.279 | 0.330 | 1.05 | CR-1B |
| David Ortiz | 164 | 23 | 33 | 0.275 | 0.360 | 2.06 | DH |
| Jeremy Hermida | 138 | 11 | 25 | 0.203 | 0.254 | 0.57 | RF |
| Darnell McDonald | 124 | 11 | 13 | 0.273 | 0.331 | -0.37 | CF-RF-LF |
| Bill Hall | 92 | 12 | 10 | 0.218 | 0.326 | 0.17 | LF-2B |
| Mike Lowell | 76 | 4 | 10 | 0.239 | 0.329 | -0.30 | 1B-DH |
| Jason Varitek | 74 | 13 | 12 | 0.269 | 0.338 | 0.90 | CR |
| Mike Cameron | 54 | 6 | 2 | 0.277 | 0.370 | -0.42 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 72.7 | 2.97 | 11 | 0 | X | 1.87 |
| John Lackey | 67.3 | 4.95 | 11 | 0 | X | -1.36 |
| Clay Buchholz | 62.7 | 2.73 | 10 | 0 | X | 1.97 |
| Tim Wakefield | 52.3 | 5.68 | 7 | 4 | X | -1.95 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daisuke Matsuzaka | 41.0 | 5.49 | 7 | 0 | X | -1.35 |
| Daniel Bard | 28.3 | 1.91 | 0 | 27 | X | 1.44 |
| Manny Delcarmen | 26.0 | 1.73 | 0 | 22 | X | 1.42 |
| Jonathan Papelbon | 23.0 | 3.13 | 0 | 21 | X | 0.51 |
| Ramon S. Ramirez | 20.0 | 5.85 | 0 | 20 | X | -0.83 |
| Hideki Okajima | 16.7 | 5.40 | 0 | 22 | X | -0.51 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Scott Atchison | 12.7 | 4.97 | 0 | 8 | X | -0.26 |
| Joe Nelson | 7.0 | 3.86 | 0 | 6 | X | 0.04 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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