| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 235 | 32 | 25 | 0.255 | 0.332 | 0.51 | 2B |
| Marco Scutaro | 226 | 29 | 8 | 0.260 | 0.345 | -1.38 | SS-2B |
| Kevin Youkilis | 216 | 45 | 29 | 0.305 | 0.454 | 2.74 | 1B |
| Adrian Beltre | 200 | 21 | 34 | 0.342 | 0.375 | 1.12 | 3B |
| J.D. Drew | 199 | 32 | 29 | 0.276 | 0.352 | 1.77 | RF |
| Victor Martinez | 180 | 23 | 24 | 0.257 | 0.311 | 0.74 | CR-1B |
| David Ortiz | 151 | 20 | 28 | 0.267 | 0.338 | 1.52 | DH |
| Jeremy Hermida | 135 | 11 | 25 | 0.208 | 0.259 | 0.64 | RF |
| Darnell McDonald | 111 | 9 | 13 | 0.267 | 0.315 | -0.27 | CF-RF-LF |
| Bill Hall | 82 | 8 | 9 | 0.194 | 0.280 | -0.12 | LF-2B |
| Mike Lowell | 76 | 4 | 10 | 0.239 | 0.329 | -0.30 | 1B-DH |
| Jason Varitek | 66 | 11 | 11 | 0.271 | 0.348 | 0.77 | CR |
| Mike Cameron | 50 | 3 | 0 | 0.250 | 0.340 | -0.85 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 65.7 | 3.15 | 10 | 0 | X | 1.41 |
| Clay Buchholz | 62.7 | 2.73 | 10 | 0 | X | 1.97 |
| John Lackey | 61.3 | 4.84 | 10 | 0 | X | -1.10 |
| Tim Wakefield | 52.3 | 5.68 | 7 | 4 | X | -1.95 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daisuke Matsuzaka | 34.3 | 5.77 | 6 | 0 | X | -1.36 |
| Daniel Bard | 26.0 | 2.08 | 0 | 25 | X | 1.21 |
| Manny Delcarmen | 24.0 | 1.88 | 0 | 20 | X | 1.23 |
| Jonathan Papelbon | 22.0 | 2.86 | 0 | 20 | X | 0.62 |
| Ramon S. Ramirez | 20.0 | 5.85 | 0 | 20 | X | -0.83 |
| Hideki Okajima | 16.7 | 5.40 | 0 | 22 | X | -0.52 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Scott Atchison | 12.7 | 4.97 | 0 | 8 | X | -0.27 |
| Joe Nelson | 5.0 | 5.40 | 0 | 4 | X | -0.15 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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