| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 226 | 32 | 25 | 0.265 | 0.341 | 0.74 | 2B |
| Marco Scutaro | 217 | 28 | 8 | 0.250 | 0.336 | -1.25 | SS-2B |
| Kevin Youkilis | 212 | 43 | 29 | 0.309 | 0.453 | 2.64 | 1B |
| Adrian Beltre | 192 | 20 | 34 | 0.339 | 0.370 | 1.22 | 3B |
| J.D. Drew | 191 | 32 | 29 | 0.283 | 0.361 | 1.97 | RF |
| Victor Martinez | 172 | 22 | 20 | 0.256 | 0.308 | 0.42 | CR-1B |
| David Ortiz | 143 | 19 | 27 | 0.266 | 0.336 | 1.51 | DH |
| Jeremy Hermida | 127 | 11 | 25 | 0.222 | 0.276 | 0.83 | RF |
| Darnell McDonald | 110 | 9 | 13 | 0.270 | 0.318 | -0.24 | CF-RF-LF |
| Bill Hall | 82 | 8 | 9 | 0.194 | 0.280 | -0.12 | LF-2B |
| Mike Lowell | 72 | 4 | 9 | 0.238 | 0.333 | -0.31 | 1B-DH |
| Jason Varitek | 66 | 11 | 11 | 0.271 | 0.348 | 0.78 | CR |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Mike Cameron | 44 | 3 | 0 | 0.237 | 0.341 | -0.71 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 65.7 | 3.15 | 10 | 0 | X | 1.40 |
| John Lackey | 61.3 | 4.84 | 10 | 0 | X | -1.11 |
| Clay Buchholz | 55.7 | 3.07 | 9 | 0 | X | 1.30 |
| Tim Wakefield | 48.7 | 4.44 | 6 | 4 | X | -0.42 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daisuke Matsuzaka | 34.3 | 5.77 | 6 | 0 | X | -1.36 |
| Daniel Bard | 25.0 | 2.16 | 0 | 24 | X | 1.11 |
| Manny Delcarmen | 24.0 | 1.88 | 0 | 20 | X | 1.23 |
| Jonathan Papelbon | 21.0 | 3.00 | 0 | 19 | X | 0.52 |
| Ramon S. Ramirez | 19.0 | 5.68 | 0 | 19 | X | -0.72 |
| Hideki Okajima | 16.3 | 4.41 | 0 | 21 | X | -0.13 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.49 |
| Joe Nelson | 4.3 | 6.23 | 0 | 3 | X | -0.22 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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