| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 217 | 30 | 25 | 0.270 | 0.341 | 0.72 | 2B |
| Marco Scutaro | 207 | 28 | 8 | 0.257 | 0.343 | -1.05 | SS-2B |
| Kevin Youkilis | 203 | 40 | 29 | 0.316 | 0.458 | 2.51 | 1B |
| J.D. Drew | 187 | 31 | 29 | 0.272 | 0.353 | 1.94 | RF |
| Adrian Beltre | 183 | 17 | 27 | 0.327 | 0.361 | 0.35 | 3B |
| Victor Martinez | 171 | 22 | 20 | 0.258 | 0.310 | 0.42 | CR-1B |
| David Ortiz | 134 | 17 | 25 | 0.258 | 0.328 | 1.29 | DH |
| Jeremy Hermida | 118 | 10 | 24 | 0.222 | 0.280 | 0.82 | RF |
| Darnell McDonald | 105 | 9 | 11 | 0.263 | 0.314 | -0.35 | CF-RF-LF |
| Bill Hall | 79 | 7 | 8 | 0.188 | 0.278 | -0.27 | LF-2B |
| Mike Lowell | 72 | 4 | 9 | 0.238 | 0.333 | -0.31 | 1B-DH |
| Jason Varitek | 57 | 11 | 10 | 0.294 | 0.368 | 0.88 | CR |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.00 | CF |
| Mike Cameron | 39 | 2 | 0 | 0.212 | 0.333 | -0.70 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 65.7 | 3.15 | 10 | 0 | X | 1.43 |
| Clay Buchholz | 55.7 | 3.07 | 9 | 0 | X | 1.31 |
| John Lackey | 55.0 | 5.07 | 9 | 0 | X | -1.27 |
| Tim Wakefield | 48.7 | 4.44 | 6 | 4 | X | -0.40 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.42 |
| Daisuke Matsuzaka | 29.7 | 5.76 | 5 | 0 | X | -1.16 |
| Daniel Bard | 25.0 | 2.16 | 0 | 24 | X | 1.12 |
| Manny Delcarmen | 22.0 | 2.05 | 0 | 19 | X | 1.05 |
| Jonathan Papelbon | 21.0 | 3.00 | 0 | 19 | X | 0.53 |
| Ramon S. Ramirez | 17.0 | 6.35 | 0 | 17 | X | -0.90 |
| Hideki Okajima | 15.7 | 4.60 | 0 | 20 | X | -0.19 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.49 |
| Joe Nelson | 2.0 | 4.50 | 0 | 1 | X | -0.02 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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