| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 198 | 28 | 25 | 0.275 | 0.348 | 0.93 | 2B |
| Marco Scutaro | 191 | 26 | 7 | 0.261 | 0.346 | -1.01 | SS-2B |
| Kevin Youkilis | 189 | 34 | 26 | 0.318 | 0.455 | 1.88 | 1B |
| J.D. Drew | 171 | 28 | 26 | 0.265 | 0.351 | 1.67 | RF |
| Adrian Beltre | 166 | 16 | 22 | 0.316 | 0.355 | 0.10 | 3B |
| Victor Martinez | 164 | 20 | 20 | 0.255 | 0.305 | 0.36 | CR-1B |
| David Ortiz | 122 | 14 | 21 | 0.245 | 0.311 | 0.82 | DH |
| Darnell McDonald | 104 | 9 | 11 | 0.266 | 0.317 | -0.33 | CF-RF-LF |
| Jeremy Hermida | 101 | 10 | 22 | 0.228 | 0.297 | 1.00 | RF |
| Bill Hall | 79 | 7 | 8 | 0.188 | 0.278 | -0.27 | LF-2B |
| Mike Lowell | 71 | 4 | 9 | 0.238 | 0.324 | -0.30 | 1B-DH |
| Jason Varitek | 47 | 10 | 10 | 0.317 | 0.404 | 1.00 | CR |
| Mike Cameron | 36 | 2 | 0 | 0.233 | 0.361 | -0.63 | CF |
| Jacoby Ellsbury | 30 | 6 | 1 | 0.333 | 0.333 | 0.03 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.17 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 59.7 | 3.47 | 9 | 0 | X | 0.88 |
| John Lackey | 55.0 | 5.07 | 9 | 0 | X | -1.24 |
| Clay Buchholz | 49.7 | 3.26 | 8 | 0 | X | 0.98 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.40 |
| Tim Wakefield | 40.7 | 5.31 | 5 | 4 | X | -1.15 |
| Daniel Bard | 22.0 | 2.45 | 0 | 21 | X | 0.85 |
| Daisuke Matsuzaka | 21.7 | 7.89 | 4 | 0 | X | -1.91 |
| Manny Delcarmen | 21.0 | 2.14 | 0 | 18 | X | 0.96 |
| Jonathan Papelbon | 20.0 | 3.15 | 0 | 18 | X | 0.45 |
| Ramon S. Ramirez | 16.0 | 5.06 | 0 | 16 | X | -0.36 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Hideki Okajima | 13.7 | 5.27 | 0 | 19 | X | -0.37 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.48 |
| Joe Nelson | 2.0 | 4.50 | 0 | 1 | X | -0.02 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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