| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 187 | 26 | 7 | 0.267 | 0.353 | -0.85 | SS-2B |
| Dustin Pedroia | 186 | 27 | 25 | 0.287 | 0.360 | 1.17 | 2B |
| Kevin Youkilis | 177 | 33 | 22 | 0.319 | 0.458 | 1.69 | 1B |
| J.D. Drew | 159 | 28 | 26 | 0.287 | 0.371 | 2.00 | RF |
| Adrian Beltre | 154 | 13 | 21 | 0.303 | 0.338 | 0.02 | 3B |
| Victor Martinez | 152 | 16 | 19 | 0.227 | 0.283 | 0.17 | CR-1B |
| David Ortiz | 117 | 13 | 19 | 0.248 | 0.316 | 0.66 | DH |
| Jeremy Hermida | 97 | 10 | 22 | 0.227 | 0.299 | 1.12 | RF |
| Darnell McDonald | 94 | 9 | 11 | 0.259 | 0.309 | -0.07 | CF-RF-LF |
| Bill Hall | 68 | 7 | 7 | 0.207 | 0.309 | -0.10 | LF-2B |
| Mike Lowell | 66 | 4 | 9 | 0.259 | 0.348 | -0.16 | 1B-DH |
| Jason Varitek | 47 | 10 | 10 | 0.317 | 0.404 | 1.02 | CR |
| Mike Cameron | 36 | 2 | 0 | 0.233 | 0.361 | -0.62 | CF |
| Jacoby Ellsbury | 30 | 6 | 1 | 0.333 | 0.333 | 0.04 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.15 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 50.7 | 3.91 | 8 | 0 | X | 0.18 |
| John Lackey | 50.0 | 4.86 | 8 | 0 | X | -0.94 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.45 |
| Clay Buchholz | 41.7 | 3.46 | 7 | 0 | X | 0.59 |
| Tim Wakefield | 40.7 | 5.31 | 5 | 4 | X | -1.19 |
| Daisuke Matsuzaka | 21.7 | 7.89 | 4 | 0 | X | -1.94 |
| Daniel Bard | 21.0 | 2.57 | 0 | 20 | X | 0.73 |
| Manny Delcarmen | 20.0 | 2.25 | 0 | 17 | X | 0.84 |
| Jonathan Papelbon | 20.0 | 3.15 | 0 | 18 | X | 0.42 |
| Ramon S. Ramirez | 16.0 | 5.06 | 0 | 16 | X | -0.38 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.23 |
| Hideki Okajima | 13.7 | 5.27 | 0 | 19 | X | -0.39 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.49 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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