| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 176 | 25 | 25 | 0.289 | 0.358 | 1.17 | 2B |
| Marco Scutaro | 172 | 23 | 7 | 0.265 | 0.355 | -0.83 | SS-2B |
| Kevin Youkilis | 163 | 29 | 17 | 0.302 | 0.448 | 1.05 | 1B |
| J.D. Drew | 146 | 25 | 22 | 0.282 | 0.370 | 1.55 | RF |
| Adrian Beltre | 146 | 13 | 20 | 0.314 | 0.349 | 0.08 | 3B |
| Victor Martinez | 144 | 14 | 17 | 0.226 | 0.285 | -0.08 | CR-1B |
| David Ortiz | 105 | 12 | 17 | 0.232 | 0.295 | 0.61 | DH |
| Jeremy Hermida | 87 | 10 | 19 | 0.228 | 0.299 | 1.03 | RF |
| Darnell McDonald | 84 | 8 | 11 | 0.240 | 0.298 | 0.05 | CF-RF-LF |
| Bill Hall | 61 | 7 | 7 | 0.235 | 0.344 | 0.06 | LF-2B |
| Mike Lowell | 61 | 4 | 9 | 0.283 | 0.377 | -0.05 | 1B-DH |
| Jason Varitek | 43 | 10 | 10 | 0.342 | 0.419 | 1.10 | CR |
| Mike Cameron | 36 | 2 | 0 | 0.233 | 0.361 | -0.62 | CF |
| Jacoby Ellsbury | 30 | 6 | 1 | 0.333 | 0.333 | 0.04 | CF |
| Jonathan Van Every | 19 | 4 | 1 | 0.176 | 0.263 | 0.08 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 50.7 | 3.91 | 8 | 0 | X | 0.18 |
| John Lackey | 43.0 | 4.60 | 7 | 0 | X | -0.55 |
| Clay Buchholz | 41.7 | 3.46 | 7 | 0 | X | 0.59 |
| Josh Beckett | 41.0 | 7.46 | 7 | 0 | X | -3.26 |
| Tim Wakefield | 38.3 | 5.63 | 5 | 3 | X | -1.41 |
| Daniel Bard | 19.7 | 2.75 | 0 | 18 | X | 0.60 |
| Manny Delcarmen | 18.7 | 2.41 | 0 | 16 | X | 0.72 |
| Jonathan Papelbon | 18.3 | 1.47 | 0 | 16 | X | 1.11 |
| Daisuke Matsuzaka | 17.0 | 6.35 | 3 | 0 | X | -0.91 |
| Ramon S. Ramirez | 15.0 | 5.40 | 0 | 15 | X | -0.47 |
| Hideki Okajima | 13.0 | 5.54 | 0 | 18 | X | -0.45 |
| Scott Schoeneweis | 12.7 | 8.53 | 0 | 14 | X | -1.32 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.49 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.33 |
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