| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 138 | 18 | 21 | 0.303 | 0.348 | 0.88 | 2B |
| Marco Scutaro | 132 | 17 | 7 | 0.284 | 0.356 | -0.56 | SS-2B |
| Kevin Youkilis | 127 | 24 | 15 | 0.295 | 0.409 | 1.13 | 1B |
| J.D. Drew | 116 | 19 | 17 | 0.253 | 0.345 | 1.08 | RF |
| Victor Martinez | 113 | 12 | 12 | 0.252 | 0.319 | -0.11 | CR-1B |
| Adrian Beltre | 112 | 10 | 16 | 0.343 | 0.375 | 0.12 | 3B |
| David Ortiz | 79 | 8 | 7 | 0.171 | 0.266 | -0.27 | DH |
| Jeremy Hermida | 66 | 8 | 16 | 0.250 | 0.318 | 0.98 | RF |
| Darnell McDonald | 54 | 7 | 9 | 0.267 | 0.352 | 0.42 | CF-RF-LF |
| Mike Lowell | 51 | 4 | 9 | 0.295 | 0.392 | 0.18 | 1B-DH |
| Bill Hall | 48 | 5 | 3 | 0.237 | 0.375 | -0.28 | LF-2B |
| Jason Varitek | 37 | 8 | 9 | 0.324 | 0.378 | 0.92 | CR |
| Mike Cameron | 36 | 2 | 0 | 0.233 | 0.361 | -0.63 | CF |
| Jacoby Ellsbury | 30 | 6 | 1 | 0.333 | 0.333 | 0.04 | CF |
| Jonathan Van Every | 11 | 1 | 1 | 0.182 | 0.182 | -0.05 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| John Lackey | 37.0 | 3.89 | 6 | 0 | X | 0.17 |
| Jon Lester | 36.7 | 3.93 | 6 | 0 | X | 0.14 |
| Josh Beckett | 35.7 | 6.31 | 6 | 0 | X | -1.85 |
| Clay Buchholz | 30.3 | 2.97 | 5 | 0 | X | 0.79 |
| Tim Wakefield | 27.3 | 6.59 | 4 | 1 | X | -1.59 |
| Daniel Bard | 16.7 | 2.70 | 0 | 15 | X | 0.54 |
| Jonathan Papelbon | 15.0 | 1.80 | 0 | 14 | X | 0.80 |
| Ramon S. Ramirez | 13.7 | 5.27 | 0 | 12 | X | -0.38 |
| Manny Delcarmen | 13.7 | 1.98 | 0 | 12 | X | 0.67 |
| Scott Schoeneweis | 10.7 | 6.75 | 0 | 11 | X | -0.66 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.48 |
| Daisuke Matsuzaka | 10.0 | 9.90 | 2 | 0 | X | -1.36 |
| Hideki Okajima | 8.7 | 6.23 | 0 | 13 | X | -0.43 |
_